Potential pathologic contribution of miRNAs to diseased state of liver in whitefish exposed to MC-LR.

<p>(A) Top ten functional GO terms (Biological process) of the 5 <i>miRNA</i> genes found deregulated in diseased liver of both human and whitefish (MC-LR). RE; Relative enrichment with respective miRNA modules [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0158899#pone.0158899.ref054" target="_blank">54</a>]. (B) A simplified network showing the relationship among 5 miRNAs (MIR92a(b)-3p, MIR122-5p, MIR146a-5p, MIR148a-3p, MIR221-3p) found to be deregulated in the diseased human liver (Ingenuity® Pathway Analysis) and in the liver of whitefish exposed to MC-LR (this study).