<i>chdp-1</i> promotes cell protrusion.

<p>(A) The PLM cell body displays a spindle-like cell shape in wild type. (B-C) Ectopic cell protrusions (arrowheads) appear on PLM cells (outlined by yellow dashed lines) when <i>chdp-1</i> is over-expressed (<i>OE chdp-1</i>). PLM is labeled by P<i>unc-86</i>::Myr::GFP. (D) Quantification of PLM cells in wild type and <i>chdp-1</i> overexpression animals with ectopic protrusions. (E) GFP::CHDP-1 co-localizes with the plasma membrane marker Myr::mCherry on ectopic protrusions. (F) Some protrusions contain actin (arrows) and some do not (arrowheads). (G) Quantification of protrusion size with or without actin. n ≥ 30. (H-I) The stress-fiber-like structures (H) disappear in <i>chdp-1</i> overexpression animals (<i>OE chdp-1</i>) (I). On the confocal images, asterisks label the nuclei within cell bodies. Data are presented as mean ± SD; ***p < 0.001.