Extracellular pH modulates mitochondrial potential.
- Joseph E. Ippolito (523145)
- Matthew W. Brandenburg (3149598)
- Xia Ge (2115646)
- Jan R. Crowley (13141)
- Kristopher M. Kirmess (3149595)
- Avik Som (1469344)
- D. Andre D’Avignon (3149601)
- Jeffrey M. Arbeit (159402)
- Samuel Achilefu (331507)
- Kevin E. Yarasheski (320459)
- Jeffrey Milbrandt (264401)
Publication date
July 2016
DOIAbstract
<p>Tetramethylrhodamine (TMRM) staining of PNEC cells following 24 hours of incubation at given pH values demonstrate increasing mitochondrial potential with increasing extracellular pH. (A-C) Photomicrographs of TMRM (red) staining of PNEC cells (Hoechst nuclear stain = blue). (D) Quantified TMRM intensity as a function of pH. Statistical comparisons for TMRM performed relative to pH 7.4. N = 10 samples per group. *p<0.05. A.U.: arbitrary units.</p
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