Body Weight and blood glucose measurements in AMPK WT and KO mice.

<p><b>A–D</b>, throughout the experiment there was no difference in body weight or volume of water consumed comparing genotype or treatment. Arrows indicate MPTP injections. <b>E–H</b>, Plasma analysis of insulin and glucose levels in trunk blood show no differences between genotype and treatment. During an oGTT Metformin treatment does not alter glucose clearance in AMPK WT (<b>I & J</b>) or AMPK KO mice (<b>K & L)</b>. Insulin sensitivity is not altered during an ITT in AMPK WT (<b>M</b>) or KO (<b>N</b>) mice treated with Metformin. * = p<0.05. Data are represented as mean ± SEM (n = 8–10, two-way ANOVA, p<0.05).