Private runs of homozygosity for LS-unaffected Lundehund in 500-SNP windows. The chromosomal position of ROH regions, number of SNPs in these regions (n), size in base pairs (size_bp), canine genes (gene) and human orthologues (human gene) are shown. (XLSX 65 kb
Table S6. Information on all large >â 5-Mb homozygous regions per patient, detected in the exome....
Table S1. Homozygous variants from a Sall2 +/â littermate used to crossvalidate the congenic footp...
Table S4. Primers for sequencing the regions, containing DArTseq-derived SNPs. (XLSX 343 kb
Runs of homozygosity for Lundehund specific regions in 500-SNP windows. The chromosomal position of ...
Results of complex segregation analysis using regressive logistic models for LS in the Lundehund. (D...
Primer sequences used for genotyping of candidate SNPs. The two variants located in KRT3 and LEPREL1...
Manhattan plot of âlog10 P-values of the genome-wide association study for hereditary ataxia in Pa...
Figure S6. Graphical representation, for each chromosome of each analysed Czechoslovakian Wolfdog, o...
Table S1. PCR primer for selected SNPs. Table S2. Confirmation of SNP calling by PCR/Sequencing. Tab...
List of the 430 genes investigated in the couples. Additional file listing the 430 genes for severe ...
Supplementary Methods: Description of methods for pooled variant calling, gene-level tests for rare ...
Pearson correlations (y-axis) of number of ROH, mean ROH size and mean sum of ROH between array data...
Per chromosome coverage by sequencing reads. The horizontal axis shows 29 autosomes and X chromosome...
Figure S1. Screening by Sanger sequencing of animals for the generation of a Syt7 conditional allele...
The proportion of gene hits against total number of process hits for genes detected in runs of homoz...
Table S6. Information on all large >â 5-Mb homozygous regions per patient, detected in the exome....
Table S1. Homozygous variants from a Sall2 +/â littermate used to crossvalidate the congenic footp...
Table S4. Primers for sequencing the regions, containing DArTseq-derived SNPs. (XLSX 343 kb
Runs of homozygosity for Lundehund specific regions in 500-SNP windows. The chromosomal position of ...
Results of complex segregation analysis using regressive logistic models for LS in the Lundehund. (D...
Primer sequences used for genotyping of candidate SNPs. The two variants located in KRT3 and LEPREL1...
Manhattan plot of âlog10 P-values of the genome-wide association study for hereditary ataxia in Pa...
Figure S6. Graphical representation, for each chromosome of each analysed Czechoslovakian Wolfdog, o...
Table S1. PCR primer for selected SNPs. Table S2. Confirmation of SNP calling by PCR/Sequencing. Tab...
List of the 430 genes investigated in the couples. Additional file listing the 430 genes for severe ...
Supplementary Methods: Description of methods for pooled variant calling, gene-level tests for rare ...
Pearson correlations (y-axis) of number of ROH, mean ROH size and mean sum of ROH between array data...
Per chromosome coverage by sequencing reads. The horizontal axis shows 29 autosomes and X chromosome...
Figure S1. Screening by Sanger sequencing of animals for the generation of a Syt7 conditional allele...
The proportion of gene hits against total number of process hits for genes detected in runs of homoz...
Table S6. Information on all large >â 5-Mb homozygous regions per patient, detected in the exome....
Table S1. Homozygous variants from a Sall2 +/â littermate used to crossvalidate the congenic footp...
Table S4. Primers for sequencing the regions, containing DArTseq-derived SNPs. (XLSX 343 kb