The mRNA expression of anti-inflammatory markers in irradiated macrophages, cultured with RKO or SW1463 cells.

<p>Macrophages were cultured alone (-) or in the presence of RKO or SW1463 cancer cells (ccRKO or ccSW), with (IR, 5 x 2 Gy) or without (Ctr) radiation exposure. The mRNA expression of a panel of anti-inflammatory macrophage markers (<i>IL10</i>, <i>CD163</i>, <i>CCL18</i> and <i>VCAN</i>) was evaluated 6 h after irradiation. Graphs result from the relative mRNA quantification in macrophages cultured with RKO or SW1463 (<i>n</i> = 4 per each cell line), evaluated in four independent experiments. For simplicity, SW1463 cells were indicated as “SW”. * <i>P</i> < 0.05, ** <i>P</i> < 0.01, *** <i>P</i> < 0.001.