Location of interstrain synonymous and nonsynonymous polymorphisms within nucleotide alignments of <i>opa</i>.

<p>Nucleotide alignments of <i>opa</i> from Mc (<i>n</i> = 17) and Gc (<i>n</i> = 69) were analyzed for synonymous (Mc, panel a, Gc, panel c) and nonsynonymous (Mc, panel b, Gc, panel d) polymorphisms. The graph demonstrates the diversity values (Theta) present amongst sequences based on the location in the nucleotide alignment. The nucleotide diversity occurring between species is demonstrated below the figures. The lines along the top indicate the conserved regions (black line), the variable regions (dark gray boxes), and the membrane-spanning regions (light gray boxes). While the synonymous polymorphisms occurring within <i>opa</i> appear to be dependent on the strain of Mc or Gc, nonsynonymous polymorphisms occur within the same regions of the nucleotide alignment, regardless of species, and are almost exclusive to the variable regions of <i>opa</i>.