mRNA levels of Fgf21 and relevant genes in mouse primary hepatocytes after simvastatin treatment.

<p>mRNA levels of Fgf21 (<b>A</b>), Pcsk9 (<b>B</b>), Acox1 (<b>C</b>), Cyp4a10 (<b>D</b>) in primary hepatocytes treated with vehicle or simvastatin (3 different doses) for 12 hours. Data are presented as the means ±SEM from 3 individual experiments, each of which included 3 technical replicates. *P<0.05 (compared with vehicle treatment).