ETDRS grid and example 10 intra-retinal layer segmentation.

<p>(A) Standard ETDRS grid showing the foveal subfield (black). The inner ring is an average of the four parafoveal subfields (dark grey) and the outer ring of the four perifoveal subfields (light grey). (B) Screenshot of 10 layer (11 boundary) segmentation of a long-wavelength OCT image, produced by the Iowa Reference Algorithms. The left half of the image shows the image prior to segmentation. Layers 1–10 (top to bottom; as defined by the software): retinal nerve fiber layer (RNFL); ganglion cell layer (GCL); inner plexiform layer (IPL); inner nuclear layer (INL); outer plexiform layer (OPL); outer plexiform layer-Henle fiber layer to boundary of myoid and ellipsoid of inner segments (OPL-HFL ~ BMEIS); photoreceptor inner/outer segments (IS/OS); inner/outer segment junction to inner boundary of outer segment photoreceptor/retinal pigment epithelium complex (IS/OSJ ~ IB_RPE); outer segment photoreceptor/retinal pigment epithelium complex (OPR); retinal pigment epithelium (RPE).