MOESM10 of Tracing HIV-1 transmission: envelope traits of HIV-1 transmitter and recipient pairs
- Corinna Oberle (672122)
- Beda Joos (196150)
- Peter Rusert (51200)
- Nottania Campbell (3491432)
- David Beauparlant (3491435)
- Herbert Kuster (196125)
- Jacqueline Weber (767580)
- Corinne Schenkel (3491426)
- Alexandra Scherrer (3447464)
- Carsten Magnus (327831)
- Roger Kouyos (178908)
- Philip Rieder (239970)
- Barbara Niederöst (239961)
- Dominique Braun (214781)
- Jovan Pavlovic (3491420)
- Jürg Böni (36157)
- Sabine Yerly (82534)
- Thomas Klimkait (178911)
- Vincent Aubert (297526)
- Alexandra Trkola (51210)
- Karin Metzner (3491429)
- Huldrych Günthard (3491423)
Publication date
September 2016
DOIAbstract
Additional file 10: Figure S6. Transmitter and recipient viruses do not exhibit different replication fitness. Replicative capacity on PBMCs was measured over a 14 day period and different measures of replication fitness were compared between transmitter and recipient virus isolates. (a) Median area under the curve (AUC) until day 7. (b) Median absolute p24 concentration at day 7. (c) Median absolute p24 concentration at day 10. (d) Median p24 value maximally reached over the 14 day period. Values are medians of the two PBMC pools tested. Wilcoxon matched-pairs signed rank test was used to determine statistical significance
Add to ORKG