mRNA expression levels for kinases of top the 20 list for CHP-212 cells. Several members of the RAS pathway from the top-ranking hits were expressed at high levels in the parental NRAS-mutant CHP-212 line, e.g. 12.03, 3.86 and 15.93 FPKMs for MAP2K1, MAP2K6 and RAF-1 respectively. (XLSX 38Â kb
The 18 gene RAS scores, and KRAS/BRAF/NRAS mutation status for 54 CRC samples (15 “bad” samples are ...
Table S2. The top ten significantly changed Canonical Pathway based on microarray analysis. (DOC 41 ...
Table S7. Chromatin regulators dysregulated by IDH1 and CIC in LGG. |Ti| is number of tumor types wh...
Top hits for the CHP-212 cell line including genes that are not essential, not present in the top 1 ...
Top hits for the CHP-212 cell line including genes that are not essential, not present in the top 1 ...
First 1 000 most depleted genes for CHP-212 cell lines. This table shows the list of 1 000 most depl...
Correlation of sgRNA library distribution between technical replicates in HCC-827 and CHP-212 cells....
Correlation of sgRNA library distribution between technical replicates of HCC-827 and CHP-212 cells....
Table S6. Number of tumor samples with mutations in each of the 21 chromatin regulator genes in list...
a) Gene Ontology (GO) analysis and b) corresponding bar chart highlighting significantly enriched te...
Mutated genes involved in the PI3K, RAS, apoptosis, and NOTCH pathways. The heatmaps show the distri...
Figure S1. Upper: The fluorescence microscopy detects the transfection efficiency of each shRNA (KD1...
Driver circuits involving a TF and a partner driver tested across 15 tumor types. (XLS 49 kb
contains Tables S1-S9. Table S1. Results of the primary yeast screen with RAS alleles RAS1 and RAS2 ...
Table S5. Detailed information of GO analysis for the selected 20 genes. (DOCX 13Â kb
The 18 gene RAS scores, and KRAS/BRAF/NRAS mutation status for 54 CRC samples (15 “bad” samples are ...
Table S2. The top ten significantly changed Canonical Pathway based on microarray analysis. (DOC 41 ...
Table S7. Chromatin regulators dysregulated by IDH1 and CIC in LGG. |Ti| is number of tumor types wh...
Top hits for the CHP-212 cell line including genes that are not essential, not present in the top 1 ...
Top hits for the CHP-212 cell line including genes that are not essential, not present in the top 1 ...
First 1 000 most depleted genes for CHP-212 cell lines. This table shows the list of 1 000 most depl...
Correlation of sgRNA library distribution between technical replicates in HCC-827 and CHP-212 cells....
Correlation of sgRNA library distribution between technical replicates of HCC-827 and CHP-212 cells....
Table S6. Number of tumor samples with mutations in each of the 21 chromatin regulator genes in list...
a) Gene Ontology (GO) analysis and b) corresponding bar chart highlighting significantly enriched te...
Mutated genes involved in the PI3K, RAS, apoptosis, and NOTCH pathways. The heatmaps show the distri...
Figure S1. Upper: The fluorescence microscopy detects the transfection efficiency of each shRNA (KD1...
Driver circuits involving a TF and a partner driver tested across 15 tumor types. (XLS 49 kb
contains Tables S1-S9. Table S1. Results of the primary yeast screen with RAS alleles RAS1 and RAS2 ...
Table S5. Detailed information of GO analysis for the selected 20 genes. (DOCX 13Â kb
The 18 gene RAS scores, and KRAS/BRAF/NRAS mutation status for 54 CRC samples (15 “bad” samples are ...
Table S2. The top ten significantly changed Canonical Pathway based on microarray analysis. (DOC 41 ...
Table S7. Chromatin regulators dysregulated by IDH1 and CIC in LGG. |Ti| is number of tumor types wh...