Additional file 3: Table S2. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Additional file 1: of A comprehensive survey of the mutagenic impact of common cancer cytotoxics

Bernadett Szikriszt (3426851)
Ádám Póti (3426842)
Orsolya Pipek (3426839)
Marcin Krzystanek (402795)
Nnennaya Kanu (3426848)
János Molnár (438764)
Dezső Ribli (2811223)
Zoltán Szeltner (3426854)
Gábor Tusnády (3426845)
István Csabai (130985)
Zoltan Szallasi (58337)
Charles Swanton (236153)
Dávid Szüts (109906)

May 2016

Supplementary Tables. Table S1 lists the number of SNV and indel mutations found in each individual ...

Additional file 3: of Guide RNAs with embedded barcodes boost CRISPR-pooled screens

Shiyou Zhu (464020)
Zhongzheng Cao (6262205)
Zhiheng Liu (341545)
Yuan He (82781)
Yinan Wang (478812)
Pengfei Yuan (464019)
Wei Li (7081)
Feng Tian (121350)
Ying Bao (267477)
Wensheng Wei (464022)

January 2019

Table S4. Results of the human genome-scale sgRNAiBAR library screening at different MOI for the cyt...

Additional file 7: of Genome-scale CRISPR-Cas9 knockout screening in gastrointestinal stromal tumor with Imatinib resistance

Jie Cao (353200)
Jianchang Wei (5626712)
Ping Yang (56755)
Tong Zhang (103827)
Zhuanpeng Chen (5626715)
Feng He (47348)
Fang Wei (31236)
Huacui Chen (5626718)
He Hu (122225)
Junbin Zhong (5626721)
Zhi Yang (124104)
Wensong Cai (5626724)
Wanglin Li (5626727)
Qiang Wang (32383)

August 2018

Table S5. Detailed information of GO analysis for the selected 20 genes. (DOCX 13Â kb

Additional file 2: Table S1. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Michael Kiessling (3480242)
Sven Schuierer (1933723)
Silke Stertz (367516)
Martin Beibel (3480251)
Sebastian Bergling (785781)
Judith Knehr (3480248)
Walter Carbone (3480254)
Cheryl de ValliĂ¨re (3480245)
Joelle Tchinda (3480239)
Tewis Bouwmeester (4352)
Klaus Seuwen (34678)
Gerhard Rogler (139954)
Guglielmo Roma (155263)

September 2016

Correlation of sgRNA library distribution between technical replicates in HCC-827 and CHP-212 cells....

Additional file 8: Table S7. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Michael Kiessling (3480242)
Sven Schuierer (1933723)
Silke Stertz (367516)
Martin Beibel (3480251)
Sebastian Bergling (785781)
Judith Knehr (3480248)
Walter Carbone (3480254)
Cheryl de ValliĂ¨re (3480245)
Joelle Tchinda (3480239)
Tewis Bouwmeester (4352)
Klaus Seuwen (34678)
Gerhard Rogler (139954)
Guglielmo Roma (155263)

September 2016

Top hits for the CHP-212 cell line including genes that are not essential, not present in the top 1 ...

Additional file 9: Table S8. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Michael Kiessling (3480242)
Sven Schuierer (1933723)
Silke Stertz (367516)
Martin Beibel (3480251)
Sebastian Bergling (785781)
Judith Knehr (3480248)
Walter Carbone (3480254)
Cheryl de ValliĂ¨re (3480245)
Joelle Tchinda (3480239)
Tewis Bouwmeester (4352)
Klaus Seuwen (34678)
Gerhard Rogler (139954)
Guglielmo Roma (155263)

September 2016

Top hits for the CHP-212 cell line including genes that are not essential, not present in the top 1 ...

Additional file 5: Table S4. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Michael Kiessling (3480242)
Sven Schuierer (1933723)
Silke Stertz (367516)
Martin Beibel (3480251)
Sebastian Bergling (785781)
Judith Knehr (3480248)
Walter Carbone (3480254)
Cheryl de Vallière (3480479)
Joelle Tchinda (3480239)
Tewis Bouwmeester (4352)
Klaus Seuwen (34678)
Gerhard Rogler (139954)
Guglielmo Roma (155263)

September 2016

First 1 000 most depleted genes for CHP-212 cell lines. This table shows the list of 1 000 most depl...

Additional file 7: Table S6. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Michael Kiessling (3480242)
Sven Schuierer (1933723)
Silke Stertz (367516)
Martin Beibel (3480251)
Sebastian Bergling (785781)
Judith Knehr (3480248)
Walter Carbone (3480254)
Cheryl de ValliĂ¨re (3480245)
Joelle Tchinda (3480239)
Tewis Bouwmeester (4352)
Klaus Seuwen (34678)
Gerhard Rogler (139954)
Guglielmo Roma (155263)

September 2016

mRNA expression levels for kinases of top the 20 list for CHP-212 cells. Several members of the RAS ...

Additional file 3: of Structural rearrangements generate cell-specific, gene-independent CRISPR-Cas9 loss of fitness effects

Emanuel Gonรงalves (5626652)
Fiona Behan (5626649)
Sandra Louzada (188636)
Damien Arnol (1403572)
Euan Stronach (5626676)
Fengtang Yang (45334)
Kosuke Yusa (3175638)
Oliver Stegle (170916)
Francesco Iorio (408438)
Mathew Garnett (408439)

February 2019

Table S2. Mean gene copy-number ratios of cancer associated genes across the cancer cell line panel....

Additional file 2: Table S2. of CRISPR/Cas9-mediated targeted chromosome elimination

Erwei Zuo (4682140)
Xiaona Huo (4682134)
Xuan Yao (344579)
Xinde Hu (4682137)
Yidi Sun (148763)
Jianhang Yin (4682122)
Bingbing He (4682125)
Xing Wang (154377)
Linyu Shi (4682119)
Jie Ping (137209)
Yu Wei (365236)
Wenqin Ying (4682131)
Wei Wei (21173)
Wenjia Liu (118146)
Cheng Tang (439042)
Yixue Li (18673)
Jiazhi Hu (4682128)
Hui Yang (91136)

November 2017

Unique and multiple repeated sequences for targeting by a single specific sgRNA. (XLSX 9524 kb

Additional file 2: of Development of drug-inducible CRISPR-Cas9 systems for large-scale functional screening

Ning Sun (162468)
Sakina Petiwala (6486374)
Rui Wang (52434)
Charles Lu (33589)
Mufeng Hu (6486377)
Sujana Ghosh (6486380)
Yan Hao (113600)
Christopher Miller (1120)
Namjin Chung (413823)

March 2019

Table S2. Raw NGS count table for FACS-based CRISPR screening using constitutive sgRNA expression ve...

Additional file 3: Table S2. of Circuits of cancer drivers revealed by convergent misregulation of transcription factor targets across tumor types

Abel Gonzalez-Perez (280875)

January 2016

Relative enrichment of driver TFs domains for somatic mutations across approximately 7,000 tumors. (...

Additional file 3: Table S2. of A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1

Frédéric Canal (3179895)
Elodie Anthony (3461654)
Aurianne Lescure (310453)
Elaine Del Nery (310455)
Jacques Camonis (49694)
Franck Perez (259284)
Bruno Ragazzon (140444)
Christine Perret (365234)

December 2015

List of the 52 genes identified among the 687 tested genes in HT screening as important for the cell...

Additional file 1 of Small extrachromosomal circular DNA harboring targeted tumor suppressor gene mutations supports intratumor heterogeneity in mouse liver cancer induced by multiplexed CRISPR/Cas9

Tao Guo (126667)
Guo-Qiao Chen (5875136)
Xu-Fan Li (17110322)
Meng Wang (124646)
Kun-Ming Liu (1508101)
Xiao-Ying Yang (2094184)
Si-Cheng Liu (5875133)
Yi-Li Feng (5875118)
Peng-Yuan Liu (60353)
Hui Lin (161703)
An-Yong Xie (13187802)

October 2023

Additional file 1: Table S1. List of target locations with sgRNA sequences, primers for targeted PCR...

Additional file 2: of Integrated genomics approach to identify biologically relevant alterations in fewer samples

Pratik Chandrani (466705)
Pawan Upadhyay (466706)
Prajish Iyer (3514739)
Mayur Tanna (3568298)
Madhur Shetty (3568301)
Gorantala Raghuram (3568289)
Ninad Oak (3568295)
Ankita Singh (3568292)
Rohan Chaubal (3568304)
Manoj Ramteke (3568286)
Sudeep Gupta (103501)
Amit Dutt (56978)

November 2015

Additional Tables S1-S8: Copy number alterations of known genomic locations identified in HNSCC cell...

Additional file 1: of A comprehensive survey of the mutagenic impact of common cancer cytotoxics

Bernadett Szikriszt (3426851)
Ádám Póti (3426842)
Orsolya Pipek (3426839)
Marcin Krzystanek (402795)
Nnennaya Kanu (3426848)
János Molnár (438764)
Dezső Ribli (2811223)
Zoltán Szeltner (3426854)
Gábor Tusnády (3426845)
István Csabai (130985)
Zoltan Szallasi (58337)
Charles Swanton (236153)
Dávid Szüts (109906)

May 2016

Supplementary Tables. Table S1 lists the number of SNV and indel mutations found in each individual ...

Additional file 3: of Guide RNAs with embedded barcodes boost CRISPR-pooled screens

Shiyou Zhu (464020)
Zhongzheng Cao (6262205)
Zhiheng Liu (341545)
Yuan He (82781)
Yinan Wang (478812)
Pengfei Yuan (464019)
Wei Li (7081)
Feng Tian (121350)
Ying Bao (267477)
Wensheng Wei (464022)

January 2019

Table S4. Results of the human genome-scale sgRNAiBAR library screening at different MOI for the cyt...

Additional file 7: of Genome-scale CRISPR-Cas9 knockout screening in gastrointestinal stromal tumor with Imatinib resistance

Jie Cao (353200)
Jianchang Wei (5626712)
Ping Yang (56755)
Tong Zhang (103827)
Zhuanpeng Chen (5626715)
Feng He (47348)
Fang Wei (31236)
Huacui Chen (5626718)
He Hu (122225)
Junbin Zhong (5626721)
Zhi Yang (124104)
Wensong Cai (5626724)
Wanglin Li (5626727)
Qiang Wang (32383)

August 2018

Table S5. Detailed information of GO analysis for the selected 20 genes. (DOCX 13Â kb

Additional file 2: Table S1. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Michael Kiessling (3480242)
Sven Schuierer (1933723)
Silke Stertz (367516)
Martin Beibel (3480251)
Sebastian Bergling (785781)
Judith Knehr (3480248)
Walter Carbone (3480254)
Cheryl de ValliĂ¨re (3480245)
Joelle Tchinda (3480239)
Tewis Bouwmeester (4352)
Klaus Seuwen (34678)
Gerhard Rogler (139954)
Guglielmo Roma (155263)

September 2016

Correlation of sgRNA library distribution between technical replicates in HCC-827 and CHP-212 cells....

Additional file 8: Table S7. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Michael Kiessling (3480242)
Sven Schuierer (1933723)
Silke Stertz (367516)
Martin Beibel (3480251)
Sebastian Bergling (785781)
Judith Knehr (3480248)
Walter Carbone (3480254)
Cheryl de ValliĂ¨re (3480245)
Joelle Tchinda (3480239)
Tewis Bouwmeester (4352)
Klaus Seuwen (34678)
Gerhard Rogler (139954)
Guglielmo Roma (155263)

September 2016

Top hits for the CHP-212 cell line including genes that are not essential, not present in the top 1 ...

Additional file 9: Table S8. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Michael Kiessling (3480242)
Sven Schuierer (1933723)
Silke Stertz (367516)
Martin Beibel (3480251)
Sebastian Bergling (785781)
Judith Knehr (3480248)
Walter Carbone (3480254)
Cheryl de ValliĂ¨re (3480245)
Joelle Tchinda (3480239)
Tewis Bouwmeester (4352)
Klaus Seuwen (34678)
Gerhard Rogler (139954)
Guglielmo Roma (155263)

September 2016

Top hits for the CHP-212 cell line including genes that are not essential, not present in the top 1 ...

Additional file 5: Table S4. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Michael Kiessling (3480242)
Sven Schuierer (1933723)
Silke Stertz (367516)
Martin Beibel (3480251)
Sebastian Bergling (785781)
Judith Knehr (3480248)
Walter Carbone (3480254)
Cheryl de Vallière (3480479)
Joelle Tchinda (3480239)
Tewis Bouwmeester (4352)
Klaus Seuwen (34678)
Gerhard Rogler (139954)
Guglielmo Roma (155263)

September 2016

First 1 000 most depleted genes for CHP-212 cell lines. This table shows the list of 1 000 most depl...

Additional file 7: Table S6. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Michael Kiessling (3480242)
Sven Schuierer (1933723)
Silke Stertz (367516)
Martin Beibel (3480251)
Sebastian Bergling (785781)
Judith Knehr (3480248)
Walter Carbone (3480254)
Cheryl de ValliĂ¨re (3480245)
Joelle Tchinda (3480239)
Tewis Bouwmeester (4352)
Klaus Seuwen (34678)
Gerhard Rogler (139954)
Guglielmo Roma (155263)

September 2016

mRNA expression levels for kinases of top the 20 list for CHP-212 cells. Several members of the RAS ...

Additional file 3: of Structural rearrangements generate cell-specific, gene-independent CRISPR-Cas9 loss of fitness effects

Emanuel Gonรงalves (5626652)
Fiona Behan (5626649)
Sandra Louzada (188636)
Damien Arnol (1403572)
Euan Stronach (5626676)
Fengtang Yang (45334)
Kosuke Yusa (3175638)
Oliver Stegle (170916)
Francesco Iorio (408438)
Mathew Garnett (408439)

February 2019

Table S2. Mean gene copy-number ratios of cancer associated genes across the cancer cell line panel....

Additional file 2: Table S2. of CRISPR/Cas9-mediated targeted chromosome elimination

Erwei Zuo (4682140)
Xiaona Huo (4682134)
Xuan Yao (344579)
Xinde Hu (4682137)
Yidi Sun (148763)
Jianhang Yin (4682122)
Bingbing He (4682125)
Xing Wang (154377)
Linyu Shi (4682119)
Jie Ping (137209)
Yu Wei (365236)
Wenqin Ying (4682131)
Wei Wei (21173)
Wenjia Liu (118146)
Cheng Tang (439042)
Yixue Li (18673)
Jiazhi Hu (4682128)
Hui Yang (91136)

November 2017

Unique and multiple repeated sequences for targeting by a single specific sgRNA. (XLSX 9524 kb

Additional file 2: of Development of drug-inducible CRISPR-Cas9 systems for large-scale functional screening

Ning Sun (162468)
Sakina Petiwala (6486374)
Rui Wang (52434)
Charles Lu (33589)
Mufeng Hu (6486377)
Sujana Ghosh (6486380)
Yan Hao (113600)
Christopher Miller (1120)
Namjin Chung (413823)

March 2019

Table S2. Raw NGS count table for FACS-based CRISPR screening using constitutive sgRNA expression ve...

Additional file 3: Table S2. of Circuits of cancer drivers revealed by convergent misregulation of transcription factor targets across tumor types

Abel Gonzalez-Perez (280875)

January 2016

Relative enrichment of driver TFs domains for somatic mutations across approximately 7,000 tumors. (...

Additional file 3: Table S2. of A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1

Frédéric Canal (3179895)
Elodie Anthony (3461654)
Aurianne Lescure (310453)
Elaine Del Nery (310455)
Jacques Camonis (49694)
Franck Perez (259284)
Bruno Ragazzon (140444)
Christine Perret (365234)

December 2015

List of the 52 genes identified among the 687 tested genes in HT screening as important for the cell...

Additional file 1 of Small extrachromosomal circular DNA harboring targeted tumor suppressor gene mutations supports intratumor heterogeneity in mouse liver cancer induced by multiplexed CRISPR/Cas9

Tao Guo (126667)
Guo-Qiao Chen (5875136)
Xu-Fan Li (17110322)
Meng Wang (124646)
Kun-Ming Liu (1508101)
Xiao-Ying Yang (2094184)
Si-Cheng Liu (5875133)
Yi-Li Feng (5875118)
Peng-Yuan Liu (60353)
Hui Lin (161703)
An-Yong Xie (13187802)

October 2023

Additional file 1: Table S1. List of target locations with sgRNA sequences, primers for targeted PCR...

Additional file 2: of Integrated genomics approach to identify biologically relevant alterations in fewer samples

Pratik Chandrani (466705)
Pawan Upadhyay (466706)
Prajish Iyer (3514739)
Mayur Tanna (3568298)
Madhur Shetty (3568301)
Gorantala Raghuram (3568289)
Ninad Oak (3568295)
Ankita Singh (3568292)
Rohan Chaubal (3568304)
Manoj Ramteke (3568286)
Sudeep Gupta (103501)
Amit Dutt (56978)

November 2015

Additional Tables S1-S8: Copy number alterations of known genomic locations identified in HNSCC cell...

Additional file 1: of A comprehensive survey of the mutagenic impact of common cancer cytotoxics

Bernadett Szikriszt (3426851)
Ádám Póti (3426842)
Orsolya Pipek (3426839)
Marcin Krzystanek (402795)
Nnennaya Kanu (3426848)
János Molnár (438764)
Dezső Ribli (2811223)
Zoltán Szeltner (3426854)
Gábor Tusnády (3426845)
István Csabai (130985)
Zoltan Szallasi (58337)
Charles Swanton (236153)
Dávid Szüts (109906)

May 2016

Supplementary Tables. Table S1 lists the number of SNV and indel mutations found in each individual ...

Additional file 3: of Guide RNAs with embedded barcodes boost CRISPR-pooled screens

Shiyou Zhu (464020)
Zhongzheng Cao (6262205)
Zhiheng Liu (341545)
Yuan He (82781)
Yinan Wang (478812)
Pengfei Yuan (464019)
Wei Li (7081)
Feng Tian (121350)
Ying Bao (267477)
Wensheng Wei (464022)

January 2019

Table S4. Results of the human genome-scale sgRNAiBAR library screening at different MOI for the cyt...

Additional file 7: of Genome-scale CRISPR-Cas9 knockout screening in gastrointestinal stromal tumor with Imatinib resistance

Jie Cao (353200)
Jianchang Wei (5626712)
Ping Yang (56755)
Tong Zhang (103827)
Zhuanpeng Chen (5626715)
Feng He (47348)
Fang Wei (31236)
Huacui Chen (5626718)
He Hu (122225)
Junbin Zhong (5626721)
Zhi Yang (124104)
Wensong Cai (5626724)
Wanglin Li (5626727)
Qiang Wang (32383)

August 2018

Table S5. Detailed information of GO analysis for the selected 20 genes. (DOCX 13Â kb

Additional file 3: Table S2. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Abstract

Extracted data

Additional file 3: Table S2. of Identification of oncogenic driver mutations by genome-wide CRISPR-Cas9 dropout screening

Abstract

Extracted data

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