CaMKIINα inhibits the dephosphorylation of CaMKII.

<p>A: Autophosphorylated CaMKII was dephosphorylated in presence of either GST as control or GST-CaMKIINα. The same dephosphorylation condition was applied to all samples but, with and without treatment of PP1. B: Difference between the densitometric values of autoradiographic bands obtained with and without PP1 was used for calculating dephosphorylation. The values plotted are the mean ± standard deviation of data of four experiments. In each set, the intensity of the band without PP1 treatment was taken as 100% phosphorylation (p < 0.05 in two-tailed student’s t-test).