<p>The curves show the relative nuclei/cytoplasm intensity of FOXO1-GFP for BITC without (black curve) and with insulin addition (red curve). Results are presented as mean values + standard error (SEM) (n = 4). Significant differences vs control (0 μM) are labelled for *(p<0.05) and **(p<0.01) (Oneway ANOVA and posthoc Dunnett T3).</p
<div><p>(A) Dispersed Kir6.2[AAA] cells labeled with Fura-2 (340-nm image). These are mainly β-cells...
<p>(a) Reduced expression of cdk2 and cdk4; (b) reduced expression of cyclin D2, cyclin D3 and cycli...
<p>(A) Representative flow histograms depicting cell cycle distribution in wild-type HCT-116 cells (...
<p>Stimulation with insulin 100 nM, BITC 30 μM, insulin + BITC, NAC 5 mM (N acetyl cysteine), BITC +...
<p>Stably transfected human osteosarcoma cells with FOXO1-GFP (U2OS-FOXO1-GFP) treated with apigenin...
<p>Stably transfected human osteosarcoma cells with FOXO1-GFP (U2OS-FOXO1-GFP) were incubated with t...
<p>(A) Immunoblotting for FoxO1 and LC3 using lysates from MDA-MB-231 cells transiently transfected ...
<p>Relative mRNA expression levels of the insulin processing enzymes <i>Pcsk1</i> (<b>A</b>), <i>Pcs...
fbp1Δ and WT cells were precultured in 3% MM and then transferred to 0% or 3% MM. Growth curves of f...
<p>A. Schema of reporter constructs integrated into the screening MIN6 cell line. These are pSico le...
<p>A. Immunohistochemistry against FoxO1 in Mdm20-, Nat5- and Rictor-KD HEK293 cells. Panels a, d, g...
<p>(A) The average nuclear translocation response graphs for negative controls siCASP8, siCntrl#1, t...
<p>(<b>A</b>) The subcellular localization and expression level of FoxO1 in C2C12-FoxO1-wt cells at ...
<p>(<b>A–F</b>): Control;Rosa-YFP and GKO;Rosa-YFP P5 pancreata were stained for insulin (blue), YFP...
<p>Adipocytes transfected with HA-GLUT4-eGFP were serum-starved prior to stimulation with 100 nM ins...
<div><p>(A) Dispersed Kir6.2[AAA] cells labeled with Fura-2 (340-nm image). These are mainly β-cells...
<p>(a) Reduced expression of cdk2 and cdk4; (b) reduced expression of cyclin D2, cyclin D3 and cycli...
<p>(A) Representative flow histograms depicting cell cycle distribution in wild-type HCT-116 cells (...
<p>Stimulation with insulin 100 nM, BITC 30 μM, insulin + BITC, NAC 5 mM (N acetyl cysteine), BITC +...
<p>Stably transfected human osteosarcoma cells with FOXO1-GFP (U2OS-FOXO1-GFP) treated with apigenin...
<p>Stably transfected human osteosarcoma cells with FOXO1-GFP (U2OS-FOXO1-GFP) were incubated with t...
<p>(A) Immunoblotting for FoxO1 and LC3 using lysates from MDA-MB-231 cells transiently transfected ...
<p>Relative mRNA expression levels of the insulin processing enzymes <i>Pcsk1</i> (<b>A</b>), <i>Pcs...
fbp1Δ and WT cells were precultured in 3% MM and then transferred to 0% or 3% MM. Growth curves of f...
<p>A. Schema of reporter constructs integrated into the screening MIN6 cell line. These are pSico le...
<p>A. Immunohistochemistry against FoxO1 in Mdm20-, Nat5- and Rictor-KD HEK293 cells. Panels a, d, g...
<p>(A) The average nuclear translocation response graphs for negative controls siCASP8, siCntrl#1, t...
<p>(<b>A</b>) The subcellular localization and expression level of FoxO1 in C2C12-FoxO1-wt cells at ...
<p>(<b>A–F</b>): Control;Rosa-YFP and GKO;Rosa-YFP P5 pancreata were stained for insulin (blue), YFP...
<p>Adipocytes transfected with HA-GLUT4-eGFP were serum-starved prior to stimulation with 100 nM ins...
<div><p>(A) Dispersed Kir6.2[AAA] cells labeled with Fura-2 (340-nm image). These are mainly β-cells...
<p>(a) Reduced expression of cdk2 and cdk4; (b) reduced expression of cyclin D2, cyclin D3 and cycli...
<p>(A) Representative flow histograms depicting cell cycle distribution in wild-type HCT-116 cells (...