Sensitivity of grooming to mild and strong stressor exposure.

<p><b>(A)</b> Relationship between the mean duration of grooming episodes in mice tested before and immediately after being handled to color their forepaws (before: 0.32±0.05 min, after: 0.69±0.07 min (n = 47), ***p = 5.9e-6). <b>(B)</b> Relationship between the mean frequency of grooming episodes in mice tested before and immediately after handling/coloring the forepaws (before: 0.010±0.001 Hz, after: 0.012±0.001 Hz (n = 47), p = 0.051). <b>(C)</b> Relative change in the duration and frequency of grooming episodes in mice tested immediately after being handled to color their forepaws (duration: 2.68±0.22, frequency: 1.61±0.23 (n = 47)). <b>(D)</b> Relationship between the mean duration of grooming episodes in mice tested before and 20 min after being handled to color their forepaws (before: 0.25±0.02 min, after 0.33±0.06 min (n = 16), p = 0.098). <b>(E)</b> Relationship between the mean frequency of grooming episodes in mice tested before and 20 min after handling/coloring the forepaws (before: 0.015±0.002 Hz, after: 0.012±0.002 Hz (n = 16), p = 0.582). <b>(F)</b> Relative change in the duration and frequency of grooming episodes in mice monitored 20 min after handling the mice to color their forepaws (duration: 1.47±0.26, frequency: 1.14±0.23 (n = 16)). <b>(G)</b> Relationship between the mean duration of grooming episodes in mice tested before and after 5 min exposure to bright light (before: 0.20±0.03 min, after: 0.40±0.08 min (n = 24), *p = 0.014). <b>(H)</b> Relationship between the mean frequency of grooming episodes in mice tested before and after 5 min bright light exposure: 0.012±0.002 Hz, 0.011±.001 Hz (n = 24), p = 0.636). <b>(I)</b> Relative change in the duration and frequency of grooming episodes in mice exposed to bright light (duration: 2.31±0.54, frequency: 1.34±0.21 (n = 24)). <b>(J)</b> Relationship between the mean duration of grooming episodes in mice tested before and after restraint stress (before: 0.18±0.02 min, after: 0.49±0.07 min (n = 15), ***p = 8.9e-4). <b>(K)</b> Relationship between the mean frequency of grooming episodes in mice tested before and after restraint stress: 0.008±0.001 Hz, 0.013±0.002 Hz (n = 15), *p = 0.018). <b>(L)</b> Relative change in the duration and frequency of grooming episodes induced by 30 min restraint stress (duration: 3.29±0.57, frequency: 1.90±0.33 (n = 15)).