Two-phase mapping of selenotranscriptome in the cerebellum, substantia nigra, cortex, pons and hippocampus of control and PD mice.

<p>The selenotranscriptome is categorized as iodothyronine deiodinases (A), glutathione peroxidases (B), thioredoxin reductases (C), thioredoxin-like endoplasmic reticulum proteins (D), the Rdx family members (E), SelK and SelS (F), and others (G). The black and white bars indicate those with repeatability in the discovery and replication phases. *, p < 0.05, compared to control. ^#, ^##, and ^### indicates a trend of difference with percentage of change at 10–15%, 15–20%, and > 20% respectively. The left and right bars for each of the sub-brain regions denote control and PD mice, respectively.