<p>Outbreaker (<b>A</b>) and SCOTTI (<b>B</b> and <b>C</b>) provide different interpretations of the <i>K. pneumoniae</i> outbreak. <b>A)</b> “Beanbag” tree of transmission events inferred with Outbreaker. Each circle represents a host, with “PMK” removed from their name. The number on transmission arrows represents the inferred posterior probability of the event. All arrows represent direct transmissions (without intermediate non-sampled hosts, with more than 85% support) except the one from PMK9 to PMK10 which is inferred to be through at least one intermediate host. <b>B)</b> “Beanbag” tree of transmission events inferred with SCOTTI. Numbers on arrows represent the inferred posterior probabilities of the corresponding direct transmissio...
<p>Each violin plot represents the density of a statistic calculated from the results of separate an...
The case–reproduction ratio for the spread of an infectious disease is a critically important concep...
Genomic data is increasingly being used to understand infectious disease epidemiology. Isolates from...
<p>SCOTTI shows higher accuracy than Outbreaker in all scenarios except with early sampling, while O...
Exploiting pathogen genomes to reconstruct transmission represents a powerful tool in the fight agai...
Exploiting pathogen genomes to reconstruct transmission represents a powerful tool in the fight agai...
<p>Transmission divergence is defined as the number of mutations separating pathogen WGS sampled fro...
Whole-genome sequencing of pathogens from host samples becomes more and more routine during infectio...
Whole-genome sequencing of pathogens from host samples becomes more and more routine during infectio...
<p>In the present work we consider three different models of pathogen evolution within an outbreak: ...
<p><b>A) Change in accuracy of outbreak reconstruction.</b> Accuracy of outbreak reconstruction is d...
There exists significant interest in developing statistical and computational tools for inferring ‘w...
<p>This figure indicates the most supported transmission tree reconstructed by <i>outbreaker</i>. Ca...
Genetic sequence data of pathogens are increasingly used to investigate transmission dynamics in bot...
There exists significant interest in developing statistical and computational tools for inferring 'w...
<p>Each violin plot represents the density of a statistic calculated from the results of separate an...
The case–reproduction ratio for the spread of an infectious disease is a critically important concep...
Genomic data is increasingly being used to understand infectious disease epidemiology. Isolates from...
<p>SCOTTI shows higher accuracy than Outbreaker in all scenarios except with early sampling, while O...
Exploiting pathogen genomes to reconstruct transmission represents a powerful tool in the fight agai...
Exploiting pathogen genomes to reconstruct transmission represents a powerful tool in the fight agai...
<p>Transmission divergence is defined as the number of mutations separating pathogen WGS sampled fro...
Whole-genome sequencing of pathogens from host samples becomes more and more routine during infectio...
Whole-genome sequencing of pathogens from host samples becomes more and more routine during infectio...
<p>In the present work we consider three different models of pathogen evolution within an outbreak: ...
<p><b>A) Change in accuracy of outbreak reconstruction.</b> Accuracy of outbreak reconstruction is d...
There exists significant interest in developing statistical and computational tools for inferring ‘w...
<p>This figure indicates the most supported transmission tree reconstructed by <i>outbreaker</i>. Ca...
Genetic sequence data of pathogens are increasingly used to investigate transmission dynamics in bot...
There exists significant interest in developing statistical and computational tools for inferring 'w...
<p>Each violin plot represents the density of a statistic calculated from the results of separate an...
The case–reproduction ratio for the spread of an infectious disease is a critically important concep...
Genomic data is increasingly being used to understand infectious disease epidemiology. Isolates from...