Non-brain directed radiation results in global brain glucose hypometabolism.

<p>(A) FDG-PET region of interest (ROI) selection subdivided the mouse brain into 19 areas. (B). When [¹⁸F]FDG uptake was normalized by blood, significant hypometabolism was noted across all areas, * = p < 0.05. Error bars = standard error of the mean. R/LSTR = Right/Left Striatum; CTX = Cortex; R/LHIP = Right/Left Hippocampus; THA = Thalamus; CB = Cerebellum; BFS = Basal forebrain; HYP = Hypothalamus; R/LAMY = Right/Left Amygdala; BS = Brainstem; CG = Cingulum; SC = Superior colliculi; OLF = Olfactory bulb; R/LMID = Right/Left Midbrain; R/LIC = Right/Left Inferior colliculi.