<p>(A) Heat map of the shared genes with variants. Each column shows the family identification of large PC families or PC pairs of the small PC families. Each row shows the gene names and shared variants are filled with red (deleterious) or orange (nondeleterious) color. (B) Deleterious variants of the Cancer Gene Census genes. The variant status is shown. ExAC_all, MAF of all subjects in the ExAC; iJGVD, MAF in the iJGVD; HGVD, MAF in the HGVD; NA, Not applicable; PC, prostate cancer.</p
<p>Visual representation and hierarchical clustering of oncodomain hotspots on genes that were signi...
<p>A) Scatter plots show the exome and RNA allele fraction for every patient and site in our study a...
Figure S6. Heat map comparing the disease–cell-type associations identified by the GSC method and te...
<p>(A) Twenty-two genes in the seven large families remained after filtering and prioritizing. Known...
<p>A) Heatmap of number of variants per tumour group. On the y-axis the different primary tumour sit...
For each subject, genotypes of all analyzed variants are shown on a row of three heatmaps that are b...
Mutation frequency within each cancer type ranges from light red (0%) to dark red (≥ 10% of samples)...
Number of common deleterious (A) genes and (B) variants in both cohorts. (C) Details of common delet...
<p>The heatmap reflects the significance of cancer-type-specific mutation density of each domain ins...
<p>The sequence of each group following resequencing was compared with the reference genome (GRCh37/...
<p>A subset of glycan genes was identified by investigating significance of gene regulation for pati...
<p>(a) variants in whole genome of RNF213. (b) The 35kb highly variable region flanking RNF213 R4810...
<p>Genes containing variants were identified with the <i>disease association panel</i> (<b>A-C</b>) ...
A single variation in the genetic sequence within the DNA of an organism could easily lead to benefi...
<p>SNPs are shown in black/grey, insertions in red, deletions in blue, and complex variants in orang...
<p>Visual representation and hierarchical clustering of oncodomain hotspots on genes that were signi...
<p>A) Scatter plots show the exome and RNA allele fraction for every patient and site in our study a...
Figure S6. Heat map comparing the disease–cell-type associations identified by the GSC method and te...
<p>(A) Twenty-two genes in the seven large families remained after filtering and prioritizing. Known...
<p>A) Heatmap of number of variants per tumour group. On the y-axis the different primary tumour sit...
For each subject, genotypes of all analyzed variants are shown on a row of three heatmaps that are b...
Mutation frequency within each cancer type ranges from light red (0%) to dark red (≥ 10% of samples)...
Number of common deleterious (A) genes and (B) variants in both cohorts. (C) Details of common delet...
<p>The heatmap reflects the significance of cancer-type-specific mutation density of each domain ins...
<p>The sequence of each group following resequencing was compared with the reference genome (GRCh37/...
<p>A subset of glycan genes was identified by investigating significance of gene regulation for pati...
<p>(a) variants in whole genome of RNF213. (b) The 35kb highly variable region flanking RNF213 R4810...
<p>Genes containing variants were identified with the <i>disease association panel</i> (<b>A-C</b>) ...
A single variation in the genetic sequence within the DNA of an organism could easily lead to benefi...
<p>SNPs are shown in black/grey, insertions in red, deletions in blue, and complex variants in orang...
<p>Visual representation and hierarchical clustering of oncodomain hotspots on genes that were signi...
<p>A) Scatter plots show the exome and RNA allele fraction for every patient and site in our study a...
Figure S6. Heat map comparing the disease–cell-type associations identified by the GSC method and te...