<p>Fitness distributions of the five yeast collections in glucose-limited, sulfate-limited, and phosphate-limited continuous-growth conditions. The fitness of each strain is shown as a small line. The fitness distribution of the control collection is shown in grey. The thick black line represents the mean. Dashed grey lines indicate the cutoff of ±10% measured using the control collection.</p
The genes of all organisms have been shaped by selective pressures. The relationship between gene se...
AbstractBudding yeast provides a useful resource for studies of gene function. A new analysis of the...
Natural selection gives rise to biodiversity by purging the less-fit among variants that are too sim...
The outcomes of evolution are determined by which mutations occur and fix. In rapidly adapting micro...
The per-genome, per-generation rate of spontaneous mutation affecting fitness (U) and the mean fitne...
The nature of selection acting on a population is in large measure determined by the distribution of...
A: We generated a synthetic population of 5 × 103 yeast metabolisms with relative gene (expression) ...
<p>(<i>A</i>) Relative exponential growth rates (parental strain set to 1.0) in single cultures for ...
Exposing natural selection driving phenotypic and genotypic adaptive differentiation is an extraordi...
<p>The fitness distribution of the studied Keio strains at in the High and Low treatments.</p
Global quantitative analysis of genetic interactions is a powerful approach for deciphering the role...
<p>Yeast pools were grown in zinc-replete (LZM+100 µM ZnCl<sub>2</sub>) and zinc-limiting (LZM+1 µM ...
<p>Distribution of the growth phenotype of all 348,300 single gene knock-out mutants.</p
Abstract The consequence of a mutation can be influenced by the context in which it operates. For ex...
The fitness of populations adapting to new environments is expected to decline in different environm...
The genes of all organisms have been shaped by selective pressures. The relationship between gene se...
AbstractBudding yeast provides a useful resource for studies of gene function. A new analysis of the...
Natural selection gives rise to biodiversity by purging the less-fit among variants that are too sim...
The outcomes of evolution are determined by which mutations occur and fix. In rapidly adapting micro...
The per-genome, per-generation rate of spontaneous mutation affecting fitness (U) and the mean fitne...
The nature of selection acting on a population is in large measure determined by the distribution of...
A: We generated a synthetic population of 5 × 103 yeast metabolisms with relative gene (expression) ...
<p>(<i>A</i>) Relative exponential growth rates (parental strain set to 1.0) in single cultures for ...
Exposing natural selection driving phenotypic and genotypic adaptive differentiation is an extraordi...
<p>The fitness distribution of the studied Keio strains at in the High and Low treatments.</p
Global quantitative analysis of genetic interactions is a powerful approach for deciphering the role...
<p>Yeast pools were grown in zinc-replete (LZM+100 µM ZnCl<sub>2</sub>) and zinc-limiting (LZM+1 µM ...
<p>Distribution of the growth phenotype of all 348,300 single gene knock-out mutants.</p
Abstract The consequence of a mutation can be influenced by the context in which it operates. For ex...
The fitness of populations adapting to new environments is expected to decline in different environm...
The genes of all organisms have been shaped by selective pressures. The relationship between gene se...
AbstractBudding yeast provides a useful resource for studies of gene function. A new analysis of the...
Natural selection gives rise to biodiversity by purging the less-fit among variants that are too sim...