Diamond Nanoparticles Modify Curcumin Activity: <i>In Vitro</i> Studies on Cancer and Normal Cells and <i>In Ovo</i> Studies on Chicken Embryo Model - Fig 2

<p><b>HepG2 cell viability measured by mitochondrial activity depletion after DN, Cur and DN:Cur bio-complexes treatment, separately for each of the used bio-complexes the DN and Cur concentrations in each of the bio-complexes were 15, 25, 45 and 75, defining the concentrations in mg/L: A</b>–Cur15:DN45 (<i>P</i> < 0.0001 for Cur effect, <i>P</i> = < 0.0001 for DN effect, <i>P</i> = 0.4813 for Cur x DN effect); <b>B</b>–Cur25:DN75 (<i>P</i> < 0.0001 for Cur effect, <i>P</i> = 0.0001 for DN effect, <i>P</i> = 0.3422 for Cur x DN effect); <b>C–</b>Cur45:DN15 (<i>P</i> < 0.0001 for Cur effect, <i>P</i> = 0.0043 for DN effect, <i>P</i> = 0.1610 for Cur x DN effect); <b>D</b>–Cur75:DN25 (<i>P</i> < 0.0001 for Cur effect, <i>P</i> = 0.1207 for DN effect, <i>P</i> = 0.0722 for Cur x DN effect). Graphs show mean ± SD, *** <i>P</i> <0.001, for Cur effect by Bonferroni post-tests following two-way ANOVA with Cur and DN factors.