<p>The Ugi coupling reaction involves the combination of isocyanide (a), aldehyde (b), amine (c) and carboxylic acid (d) components in a single reaction step to give an α-aminoacyl amide product, as exemplified above for the preparation of AZ126.</p
The Ugi-azide reaction of an enantiopure amino acid derived isocyanides, amino acid esters, aldehyde...
A general synthesis of N-protected primary α-amino 1,3,4-oxadiazoles, from N-carbamoyl imines, N-iso...
Multicomponent coupling reactions (MCRs) are high-conversion, one-pot processes that combine three o...
The Ugi four-component reaction (Ugi-4CR) undoubtedly is the most prominent multicomponent reaction ...
Pyrrolidine and 1,2,3,4-tetrahydroisoquinoline (THIQ) undergo redox-neutral α-amidation with concurr...
Isocyanide based multicomponent reactions, including the Ugi four-component and Passerini three-comp...
Synthesis of complex, biologically active molecules is critical for the discovery and development of...
Perfect atom economy characterizes a novel catalytic three‐component Ugi reaction (see example). Dif...
With the endeavor to find new efficient synthetic methods to rapidly access diverse molecular struct...
This project focuses on a multicomponent reaction, Ugi; which is a four-component condensation react...
Amides are ubiquitous in the fine chemical, agrochemical and pharmaceutical industries, but are rare...
The Ugi four-component reaction (U-4CR) with N-hydroxyimides as a novel carboxylic acid isostere has...
Ugi type reactions are well known for decades. These multicomponent reactions involve an aldehyde,an...
A facile and efficient synthetic protocol for the synthesis of α-amino amidines has been developed u...
A synthetic strategy for the Ugi reaction on amino-β-lactam synthon 1 was developed. The Ugi reactio...
The Ugi-azide reaction of an enantiopure amino acid derived isocyanides, amino acid esters, aldehyde...
A general synthesis of N-protected primary α-amino 1,3,4-oxadiazoles, from N-carbamoyl imines, N-iso...
Multicomponent coupling reactions (MCRs) are high-conversion, one-pot processes that combine three o...
The Ugi four-component reaction (Ugi-4CR) undoubtedly is the most prominent multicomponent reaction ...
Pyrrolidine and 1,2,3,4-tetrahydroisoquinoline (THIQ) undergo redox-neutral α-amidation with concurr...
Isocyanide based multicomponent reactions, including the Ugi four-component and Passerini three-comp...
Synthesis of complex, biologically active molecules is critical for the discovery and development of...
Perfect atom economy characterizes a novel catalytic three‐component Ugi reaction (see example). Dif...
With the endeavor to find new efficient synthetic methods to rapidly access diverse molecular struct...
This project focuses on a multicomponent reaction, Ugi; which is a four-component condensation react...
Amides are ubiquitous in the fine chemical, agrochemical and pharmaceutical industries, but are rare...
The Ugi four-component reaction (U-4CR) with N-hydroxyimides as a novel carboxylic acid isostere has...
Ugi type reactions are well known for decades. These multicomponent reactions involve an aldehyde,an...
A facile and efficient synthetic protocol for the synthesis of α-amino amidines has been developed u...
A synthetic strategy for the Ugi reaction on amino-β-lactam synthon 1 was developed. The Ugi reactio...
The Ugi-azide reaction of an enantiopure amino acid derived isocyanides, amino acid esters, aldehyde...
A general synthesis of N-protected primary α-amino 1,3,4-oxadiazoles, from N-carbamoyl imines, N-iso...
Multicomponent coupling reactions (MCRs) are high-conversion, one-pot processes that combine three o...