<p>The genotype is coded for the risk increasing allele, which is the first one mentioned (e.g., A in A/C). The discovery test of ARHI in GERA non-Hispanic whites was two-sided<sup>#</sup>, and all replication tests were one-sided. There are no estimates for African American cases SDS/SRT, as the sample size was too small. OR, odds ratio (for case/control phenotypes); Effect, effect size estimate (for SDS/SRT phenotypes); Freq, frequency of the risk increasing allele; SRT, speech reception threshold; SDS, speech discrimination score.</p
The new class of rare variant tests has usually been evaluated assuming perfect genotype information...
<p>Our study design had four stages (sample sizes for cases/controls are in parentheses). In Stage 1...
<p>* Exome Aggregation Consortium (<a href="http://exac.broadinstitude.org/" target="_blank">http://...
<p>The genotype is coded for the risk increasing allele, which is the first one mentioned (e.g., T i...
<p>Note: SNPs are the set of genome-wide significant SNPs discovered in the GWAS meta-analysis by Mo...
<p>Note: Number of controls (n = 859) is the same across case analysis strata.</p><p>Abbreviations: ...
<p>Direction: RA is risk allele. The odds ratio (OR) is presented for the risk allele, compared with...
<p>Abbreviations: f<sub>CEU</sub>: frequency of modeled allele in HapMap Northern and Western Europe...
We evaluate the effect of genotyping errors on the type-I error of a general association test based ...
<p>After processing the data using the GATK pipeline, this filtering workflow was derived to identif...
Abstract Background One common goal of a case/control genome wide association study (GWAS) is to fin...
A commonly-used method for testing for association between disease and a single-nucleotide polymorph...
Complex diseases are often highly heritable. However, for many complex traits only a small proportio...
<p>The risk alleles considered are the variant alleles of rs7574865, rs3099844 and rs3024505 SNPs.</...
Complex diseases are often highly heritable. However, for many complex traits only a small proportio...
The new class of rare variant tests has usually been evaluated assuming perfect genotype information...
<p>Our study design had four stages (sample sizes for cases/controls are in parentheses). In Stage 1...
<p>* Exome Aggregation Consortium (<a href="http://exac.broadinstitude.org/" target="_blank">http://...
<p>The genotype is coded for the risk increasing allele, which is the first one mentioned (e.g., T i...
<p>Note: SNPs are the set of genome-wide significant SNPs discovered in the GWAS meta-analysis by Mo...
<p>Note: Number of controls (n = 859) is the same across case analysis strata.</p><p>Abbreviations: ...
<p>Direction: RA is risk allele. The odds ratio (OR) is presented for the risk allele, compared with...
<p>Abbreviations: f<sub>CEU</sub>: frequency of modeled allele in HapMap Northern and Western Europe...
We evaluate the effect of genotyping errors on the type-I error of a general association test based ...
<p>After processing the data using the GATK pipeline, this filtering workflow was derived to identif...
Abstract Background One common goal of a case/control genome wide association study (GWAS) is to fin...
A commonly-used method for testing for association between disease and a single-nucleotide polymorph...
Complex diseases are often highly heritable. However, for many complex traits only a small proportio...
<p>The risk alleles considered are the variant alleles of rs7574865, rs3099844 and rs3024505 SNPs.</...
Complex diseases are often highly heritable. However, for many complex traits only a small proportio...
The new class of rare variant tests has usually been evaluated assuming perfect genotype information...
<p>Our study design had four stages (sample sizes for cases/controls are in parentheses). In Stage 1...
<p>* Exome Aggregation Consortium (<a href="http://exac.broadinstitude.org/" target="_blank">http://...