Hippocampal Aβ plaques in 121 and 221 day old <i>scyllo</i>-inositol treated and untreated Tg mice.

<p>(A) Percent hippocampal area covered in plaques in 121 day old Tg (n = 5) and Tg-SI (n = 6) mice showed decreased plaques after treatment. (B) Representative images of Aβ plaques in the hippocampus of 121 day old mice demonstrate the reduction in plaques after <i>scyllo</i>-inositol treatment. (C) Percent hippocampal area covered in plaques in 221 day old Tg (n = 5) and Tg-SI (n = 6) mice also showed less plaques after treatment. (D) Representative images of Aβ plaques in the hippocampus of 221 day old mice demonstrate the reduction in plaques after <i>scyllo</i>-inositol treatment. Scale bar indicates 200 μm. Data are mean ± SEM. Unpaired t-test, * represents p< 0.05.