Expression analysis of derived NCCs compared to hiPSCs.
- Richard W. Naylor (3280731)
- Charles N. J. McGhee (3280728)
- Chad A. Cowan (146464)
- Alan J. Davidson (3280722)
- Teresa M. Holm (3280725)
- Trevor Sherwin (53421)
Publication date
October 2016
DOIAbstract
<p>Quantitative polymerase chain reaction (qPCR) analysis showed derived NCCs had higher expression of many neural crest markers relative to hiPSCs. The pluripotency markers <i>SOX2</i>, <i>OCT3/4</i> and <i>NANOG</i> were significantly reduced in NCCs, but <i>KLF4</i> expression was maintained at a similar level.</p
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