DNA double strand break repair foci.

<p>Immunofluorescence staining of spermatocyte chromosome spreads of WT, SKO and DKO mice, probed with anti-SYCP3 (red) for AEs/LEs and anti-DMC1 (green) or anti RAD51 as indicated for DNA double-strand break repair foci. Upper panel: leptotene/early zygotene stage with many DMC1 foci; middle panel: late zygotene/early pachytene like stage with reduced number of DMC1 foci; lower panel: RAD51 foci on pachytene-stage like cells (scale bar: 5 μm).