<p>Transmembrane currents into selected extracellular volumes, including (column <b>A</b>) the subvolume containing the neuronal somata (<i>n</i> = 3), (column <b>B</b>) the subvolume containing the trunk of the apical dendrite (<i>n</i> = 7), and (column <b>C</b>) the subvolume where the apical dendrites branched out (<i>n</i> = 13). Currents were subdivided into ion specific currents (row <b>1</b>–<b>4</b>) and the capacitive current (row <b>5</b>). The sum of all currents into a subvolume <i>n</i> is shown in row <b>6</b>. The location of the midpoint of a neural segment determined which ECS subvolume <i>n</i> it belonged to, and currents were summed over all neural segments (of all neurons) that occupied a given ECS-subvolume (<i>n</i>)...
<p>(A) The biophysical model. Upper panel: schematic representation of the biophysical model, where ...
Many neurons have extensive dendritic trees, and therefore somatic voltage clamp of dendritic synaps...
The relationship between the form and function of neurones has intrigued and frustrated neuroscienti...
Gray circles are quantities associated with interactions between populations (i.e., a and b), while ...
<p>The transmembrane currents are illustrated by synaptic currents and channel currents. A synaptic ...
Computational models which take into account both linear and nonlinear membrane properties were deve...
1. Computer simulations were used to study the effect of voltage-dependent calcium and potassium con...
<p><i>Top:</i> Visualization of the ball-and-stick, BS, (<i>left</i>) and the extended point, eP, (<...
ABsTRAcr Mathematical solutions and numerical illustrations are presented for the steady-state distr...
<p>(A) Synaptic input current as a function of the number of columns. Shown are the averaged values ...
A common method of measuring neural activity is to insert recording electrodes into brain tissue, as...
Action potentials generated near the soma propagate not only into the axonal nerve connecting to the...
<p>A homogeneous density of noisy input currents is applied throughout the neural membrane. Columns ...
<p>(A) A simplified schematic of the spatial polarization in the neuron induced by extracellular ele...
AbstractAction potentials generated near the soma propagate not only into the axonal nerve connectin...
<p>(A) The biophysical model. Upper panel: schematic representation of the biophysical model, where ...
Many neurons have extensive dendritic trees, and therefore somatic voltage clamp of dendritic synaps...
The relationship between the form and function of neurones has intrigued and frustrated neuroscienti...
Gray circles are quantities associated with interactions between populations (i.e., a and b), while ...
<p>The transmembrane currents are illustrated by synaptic currents and channel currents. A synaptic ...
Computational models which take into account both linear and nonlinear membrane properties were deve...
1. Computer simulations were used to study the effect of voltage-dependent calcium and potassium con...
<p><i>Top:</i> Visualization of the ball-and-stick, BS, (<i>left</i>) and the extended point, eP, (<...
ABsTRAcr Mathematical solutions and numerical illustrations are presented for the steady-state distr...
<p>(A) Synaptic input current as a function of the number of columns. Shown are the averaged values ...
A common method of measuring neural activity is to insert recording electrodes into brain tissue, as...
Action potentials generated near the soma propagate not only into the axonal nerve connecting to the...
<p>A homogeneous density of noisy input currents is applied throughout the neural membrane. Columns ...
<p>(A) A simplified schematic of the spatial polarization in the neuron induced by extracellular ele...
AbstractAction potentials generated near the soma propagate not only into the axonal nerve connectin...
<p>(A) The biophysical model. Upper panel: schematic representation of the biophysical model, where ...
Many neurons have extensive dendritic trees, and therefore somatic voltage clamp of dendritic synaps...
The relationship between the form and function of neurones has intrigued and frustrated neuroscienti...