<p>Representative microscopic features of the cartilage defect area in the control group (defect only) and experimental groups (0.1 x 10<sup>7</sup> cells/ml, 0.5 x 10<sup>7</sup> cells/ml, 1.0 x 10<sup>7</sup> cells/ml, 1.5 x 10<sup>7</sup> cells/ml) at 16 weeks post transplantation. Sectioned specimens were stained with H & E, safranin-O, Collagen type II antibody, and Masson’s Trichrome. × 40. Scale bars = 200 μm.</p
<p>Discs grown from the MSCs of a healthy donor (donor C; panel A) and an OA patient (patient D; pan...
Background: Our goal was to set up an ex vivo culture system to assess whether cartilage wounding (p...
<p>Coronal plane sections were stained with hematoxylin and eosin (H&E). For each group, the left pa...
<p>H&E staining of cartilage sections (scar bar = 100 μm) (A), the modified OARSI score of microscop...
<p>Using the modified O`Driscoll scoring scale, cartilage repair at the defect site was quantified i...
<p>Representative results of histologic evaluation of the regenerative tissues stained with toluidin...
<p>Macroscopic and microscopic images of regenerated cartilage at 8 weeks. A: C group (Control); B: ...
<p>Longitudinal section of distal femur indicating the region of interest (black box and yellow box ...
<p>Immunohistological staining of regenerative tissues 4 weeks after transplantation of non-transfec...
<p>(A–B) Fibrocartilaginous tissue in SED group. The extracellular matrix was poorly organized. (C–D...
none8noneMarconi E.; Grigolo B.; Roseti L.; De Franceschi L.; Desando G.; Manfredini M.; Faccini R.;...
<p>Representative sections from the 5 groups at 6 (A–E) and 12 weeks (F–J) post-transplantation. (K)...
Explants stained with H&E (A) or safranin O (B). Bar graphs (C) represent the color intensity of saf...
<p>(A,E,I,M,Q,U) H&E staining. (B,F,J,N,R,V) Toluidine blue staining. (C,G,K,O,S,W) Safranin O stain...
<p>(A–B) Fibrous tissue in SED group. The spindle-shaped fibroblasts embeded in thin fibrin-like tis...
<p>Discs grown from the MSCs of a healthy donor (donor C; panel A) and an OA patient (patient D; pan...
Background: Our goal was to set up an ex vivo culture system to assess whether cartilage wounding (p...
<p>Coronal plane sections were stained with hematoxylin and eosin (H&E). For each group, the left pa...
<p>H&E staining of cartilage sections (scar bar = 100 μm) (A), the modified OARSI score of microscop...
<p>Using the modified O`Driscoll scoring scale, cartilage repair at the defect site was quantified i...
<p>Representative results of histologic evaluation of the regenerative tissues stained with toluidin...
<p>Macroscopic and microscopic images of regenerated cartilage at 8 weeks. A: C group (Control); B: ...
<p>Longitudinal section of distal femur indicating the region of interest (black box and yellow box ...
<p>Immunohistological staining of regenerative tissues 4 weeks after transplantation of non-transfec...
<p>(A–B) Fibrocartilaginous tissue in SED group. The extracellular matrix was poorly organized. (C–D...
none8noneMarconi E.; Grigolo B.; Roseti L.; De Franceschi L.; Desando G.; Manfredini M.; Faccini R.;...
<p>Representative sections from the 5 groups at 6 (A–E) and 12 weeks (F–J) post-transplantation. (K)...
Explants stained with H&E (A) or safranin O (B). Bar graphs (C) represent the color intensity of saf...
<p>(A,E,I,M,Q,U) H&E staining. (B,F,J,N,R,V) Toluidine blue staining. (C,G,K,O,S,W) Safranin O stain...
<p>(A–B) Fibrous tissue in SED group. The spindle-shaped fibroblasts embeded in thin fibrin-like tis...
<p>Discs grown from the MSCs of a healthy donor (donor C; panel A) and an OA patient (patient D; pan...
Background: Our goal was to set up an ex vivo culture system to assess whether cartilage wounding (p...
<p>Coronal plane sections were stained with hematoxylin and eosin (H&E). For each group, the left pa...