Determination of NCX current in dog ventricular myocytes.
- Zsófia Kohajda (291183)
- Nikolett Farkas-Morvay (3342650)
- Norbert Jost (291188)
- Norbert Nagy (1413259)
- Amir Geramipour (3342674)
- András Horváth (159844)
- Richárd S. Varga (3342659)
- Tibor Hornyik (3342668)
- Claudia Corici (3342647)
- Károly Acsai (3342656)
- Balázs Horváth (438763)
- János Prorok (376409)
- Balázs Ördög (3342644)
- Szilvia Déri (3342665)
- Dániel Tóth (3342638)
- Jouko Levijoki (3342653)
- Piero Pollesello (725168)
- Tuula Koskelainen (3342641)
- Leena Otsomaa (3342662)
- András Tóth (50203)
- István Baczkó (291190)
- István Leprán (3342671)
- Péter P. Nánási (3342635)
- Julius Gy Papp (291192)
- András Varró (219743)
- László Virág (219742)
DOIAbstract
<p>The protocol was adapted from Hobai <i>et al</i> [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0166041#pone.0166041.ref027" target="_blank">27</a>]. <b>A:</b> Recording obtained with the voltage protocol shown in the inset in control conditions (current trace after blockade of Na<sup>+</sup>, Ca<sup>2+</sup>, K<sup>+</sup> and Na<sup>+</sup>/K<sup>+</sup> pump currents. <b>B:</b> The current trace after superfusion with 100 nM ORM-10962. <b>C:</b> The current trace at the end of the measurements after the application of 10 mM NiCl<sub>2</sub>. On the right the control NCX current is shown, which is obtained by subtracting trace <b>C</b> from trace <b>A</b>. The NCX current in the presence of 100 nM ORM-10962 is o...
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