CT scan images of orthotopic tumor in mouse abdomen.

<p>Yellow line outlines the tumor. (a) Pre contrast injection. (b) immediately post contrast injection, showing the abdominal vasculature including vessels within the tumor. (c) 5 days post contrast injection, showing extravasated contrast within the tumor margin, and highlighting the liver and spleen, organs of the reticulo-endothelial system (RES) involved in clearance of the contrast agent. (d) After a 2^nd dose of contrast, thus depicting both the vasculature and the intratumoral extravasate.