<p>Depicted is the mean fluorescence intensity as analyzed by flow cytometry using monoclonal antibodies for ceramide, lactosylceramide globotriaosylceramide and dodecasaccharideceramide, and cholera toxin subunit B for ganglioside GM1 after MCSF differentiation (d4) and lipoprotein loading (d6) with eLDL, oxLDL or control (MCSF) <b>(A)</b> ceramide, <b>(B)</b> lactosylceramide/CDw17, <b>(C)</b> globotriaosylceramide, <b>(D)</b> dodecasaccharideceramide and <b>(E)</b> GM1 ganglioside. n = 3. Data on surface ceramide and lactosylceramide have been published previously [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0166798#pone.0166798.ref013" target="_blank">13</a>].</p
Glucosylceramide synthase (GCS or GlcT-1), converting ceramide to glucosylceramide, is a key enzyme ...
Sphingolipids including ceramides and its derivatives such as ceramide-1-phosphate, glucosylceramide...
A novel MALDI-FTICR imaging mass spectrometry (MALDI-IMS) workflow is described for on-tissue detect...
Glycosphingolipids (GSLs) are composed of hydrophobic ceramide and hydrophilic sugar chains. GSLs cl...
A murine monoclonal antibody (IgMκ), termed 3D10, was established by fusion of P3X63Ag8.653 mouse my...
Gangliosides in the outer leaflet of the plasma membrane of eukaryotic cells are essential for many ...
Background/Aims: The activation of acid sphingomyelinase by cellular stress or receptors or the de n...
Sphingolipids have long been identified as bioactive lipids thus participating in cell regulation an...
Ceramide is a sphingolipid that is composed of a long-chain derived from plants are mostly glucosyla...
Sphingolipids consist of a sphingoid base N-linked to a fatty acyl chain. Among them, sphingomyelins...
<p>The biosynthetic pathway of sphingolipids relevant to this study is shown. Underlining indicates ...
AbstractCeramide is a sphingolipid present in eukaryotic cells that laterally segregates into solid ...
<p>(<b>A</b>) Diagram depicting the <i>de novo</i> synthesis pathway of (glucosyl)ceramides. Loss-of...
Ceramide is a key lipid molecule necessary to regulate some cellular processes, including apoptosis ...
<p>(A) Glucosylceramide (GC) was increased in GD2-8760 iPSCs, GD2-1260 NPCs and neurons and GD2-2627...
Glucosylceramide synthase (GCS or GlcT-1), converting ceramide to glucosylceramide, is a key enzyme ...
Sphingolipids including ceramides and its derivatives such as ceramide-1-phosphate, glucosylceramide...
A novel MALDI-FTICR imaging mass spectrometry (MALDI-IMS) workflow is described for on-tissue detect...
Glycosphingolipids (GSLs) are composed of hydrophobic ceramide and hydrophilic sugar chains. GSLs cl...
A murine monoclonal antibody (IgMκ), termed 3D10, was established by fusion of P3X63Ag8.653 mouse my...
Gangliosides in the outer leaflet of the plasma membrane of eukaryotic cells are essential for many ...
Background/Aims: The activation of acid sphingomyelinase by cellular stress or receptors or the de n...
Sphingolipids have long been identified as bioactive lipids thus participating in cell regulation an...
Ceramide is a sphingolipid that is composed of a long-chain derived from plants are mostly glucosyla...
Sphingolipids consist of a sphingoid base N-linked to a fatty acyl chain. Among them, sphingomyelins...
<p>The biosynthetic pathway of sphingolipids relevant to this study is shown. Underlining indicates ...
AbstractCeramide is a sphingolipid present in eukaryotic cells that laterally segregates into solid ...
<p>(<b>A</b>) Diagram depicting the <i>de novo</i> synthesis pathway of (glucosyl)ceramides. Loss-of...
Ceramide is a key lipid molecule necessary to regulate some cellular processes, including apoptosis ...
<p>(A) Glucosylceramide (GC) was increased in GD2-8760 iPSCs, GD2-1260 NPCs and neurons and GD2-2627...
Glucosylceramide synthase (GCS or GlcT-1), converting ceramide to glucosylceramide, is a key enzyme ...
Sphingolipids including ceramides and its derivatives such as ceramide-1-phosphate, glucosylceramide...
A novel MALDI-FTICR imaging mass spectrometry (MALDI-IMS) workflow is described for on-tissue detect...