Representative Three-dimensional Trabecular Architecture of the Tibia After <i>Pth1r</i> or <i>Igf-1r</i> siRNA Injection.
- Wen Zhang (7555)
- Can Liu (205007)
- Bao Hai (3366692)
- Guohong Du (3366695)
- Hong Wang (13528)
- Huijie Leng (494783)
- Yingsheng Xu (3366698)
- Chunli Song (2023402)
Publication date
November 2016
DOIAbstract
<p>In the <i>Igf-1r</i> siRNA transfection groups, the trabeculae in the left tibias treated with <i>Igf-1r</i> siRNA and IGF-1 were dramatically weakened compared to those in the right tibias treated with IGF-1 only. In the <i>Pth1r</i> siRNA transfection groups, the trabeculae in the left tibias treated with <i>Pth1r</i> siRNA and rhPTH (1–34) were also significantly weakened compared to those in the right tibias treated with rhPTH (1–34) only.</p