Pharmacokinetic parameters of verdinexor following a per os dose of 5 mg/kg in male ferrets.

Main pharmacokinetic parameters (mean±SD) after oral administration of DAS (25 mg/kg) to rats (n = 5).

Hadir M. Maher (5394977)
Nourah Z. Alzoman (5394980)
Shereen M. Shehata (5394971)
Norah O. Abanmy (5394974)

June 2018

Main pharmacokinetic parameters (mean±SD) after oral administration of DAS (25 mg/kg) to rats (<i...

Pharmacokinetic parameters for phenylbenzamides after 1 mg/kg intravenous injection or 5mg/kg oral dose in Sprague Dawley rats.

Hiral A. Bhagat (5896475)
Sarah A. Compton (5896478)
David L. Musso (3012933)
Christopher P. Laudeman (2425168)
Kimberly M. P. Jackson (5896481)
Na Young Yi (5896484)
Lidia S. Nierobisz (5896487)
Lawrence Forsberg (5896490)
Jay E. Brenman (241583)
Jonathan Z. Sexton (2263105)

October 2018

Pharmacokinetic parameters for phenylbenzamides after 1 mg/kg intravenous injection or 5mg/kg oral d...

Summary of Pharmacokinetic Parameters for Zanamivir from Different Formulations after Intraduodenal Administration in Male Sprague-Dawley Rats at 1.5 mg/animal.

Eric H. Holmes (403612)
Harikrishna Devalapally (403613)
Libin Li (403614)
Michael L. Perdue (403615)
Gary K. Ostrander (403616)

April 2013

Cmax: Maximum plasma concentration; tmax: Time to maximum plasma concentrat...

OC PK parameters estimated in ferrets with and without anesthesia.

Micaela B. Reddy (384270)
Kuo-Hsiung Yang (650738)
Gauri Rao (812523)
Craig R. Rayner (384272)
Jing Nie (139250)
Chandrasena Pamulapati (812524)
Bindumadhav M. Marathe (446548)
Alan Forrest (210305)
Elena A. Govorkova (44419)

October 2015

a The CL and V parameters are conditioned on oral bioavailability and fraction of pare...

Oseltamivir Population Pharmacokinetics in the Ferret: Model Application for Pharmacokinetic/Pharmacodynamic Study Design

Micaela B. Reddy (384270)
Kuo-Hsiung Yang (650738)
Gauri Rao (812523)
Craig R. Rayner (384272)
Jing Nie (139250)
Chandrasena Pamulapati (812524)
Bindumadhav M. Marathe (446548)
Alan Forrest (210305)
Elena A. Govorkova (44419)

October 2015

<div>The ferret is a suitable small animal model for preclinical evaluation of efficacy of antivi...

Oseltamivir Population Pharmacokinetics in the Ferret: Model Application for Pharmacokinetic/Pharmacodynamic Study Design.

Micaela B Reddy
Kuo-Hsiung Yang
Gauri Rao
Craig R Rayner
Jing Nie
Chandrasena Pamulapati
Bindumadhav M Marathe
Alan Forrest
Elena A Govorkova

The ferret is a suitable small animal model for preclinical evaluation of efficacy of antiviral drug...

OP and OC PK parameters in uninfected ferrets following an oral dose of oseltamivir.a

Micaela B. Reddy (384270)
Kuo-Hsiung Yang (650738)
Gauri Rao (812523)
Craig R. Rayner (384272)
Jing Nie (139250)
Chandrasena Pamulapati (812524)
Bindumadhav M. Marathe (446548)
Alan Forrest (210305)
Elena A. Govorkova (44419)

October 2015

a This PK analysis used data from uninfected animals (e.g., from Study 1, uninfected f...

Pharmacokinetic parameters of aniracetam and N-anisoyl-GABA following oral administration of aniracetam to pigeons.

Hannah Phillips (6616406)
Arlene McDowell (6616409)
Birgitte S. Mielby (6616412)
Ian G. Tucker (2382481)
Michael Colombo (27205)

April 2019

Pharmacokinetic parameters of aniracetam and N-anisoyl-GABA following oral administration of anirace...

Verdinexor treatment reduces immune cell infiltration and pro-inflammatory cytokine expression and in influenza-infected ferrets.

Olivia Perwitasari (2742820)
Scott Johnson (150270)
Xiuzhen Yan (166271)
Emery Register (3366842)
Jackelyn Crabtree (425215)
Jon Gabbard (645849)
Elizabeth Howerth (3366836)
Sharon Shacham (519876)
Robert Carlson (2044168)
Sharon Tamir (3366839)
Ralph A. Tripp (166289)

November 2016

Ferrets were i.n. infected with 10×ID50 A/California/04/09 and orally treated with 15 ...

Pharmacokinetic parameters of evocalcet after oral administration to male rats.

Takehisa Kawata (5052257)
Shin Tokunaga (5052263)
Miki Murai (2654710)
Nami Masuda (5052245)
Waka Haruyama (5052260)
Youji Shoukei (5052248)
Yutaka Hisada (5052251)
Tetsuya Yanagida (580156)
Hiroshi Miyazaki (459162)
Michihito Wada (5052254)
Tadao Akizawa (316095)
Masafumi Fukagawa (721664)

April 2018

Pharmacokinetic parameters of evocalcet after oral administration to male rats.</p

OC PK parameters estimated in uninfected and influenza virus-infected ferrets.

Micaela B. Reddy (384270)
Kuo-Hsiung Yang (650738)
Gauri Rao (812523)
Craig R. Rayner (384272)
Jing Nie (139250)
Chandrasena Pamulapati (812524)
Bindumadhav M. Marathe (446548)
Alan Forrest (210305)
Elena A. Govorkova (44419)

October 2015

a The CL and V parameters are conditioned on oral bioavailability and fraction of pare...

Pharmacokinetic parameters determined for a treatment schedule of four applications of diminazene (at 5 mg/kg), DB 75, DB 867 and DB 1192 (at 2.5 mg/kg and 1.25 mg/kg), based on average plasma concentration levels taken from T. evansi experimentally infected goats.

Kirsten Gillingwater (349563)
Carlos Gutierrez (349565)
Arlene Bridges (349566)
Huali Wu (349567)
Stijn Deborggraeve (56957)
Rosine Ali Ekangu (246157)
Arvind Kumar (227201)
Mohamed Ismail (349568)
David Boykin (349569)
Reto Brun (41511)

February 2013

Pharmacokinetic parameters determined for a treatment schedule of four applications of diminazene...

Mean manual activity score of non-infected ferrets and infected ferrets with or without oseltamivir treatment from day 0 to day 11 post-infection.

Ding Yuan Oh (324894)
Ian G. Barr (216006)
Aeron C. Hurt (215989)

March 2015

OST: OseltamivirMean manual activity score of non-infected ferrets and infected ferrets wi...

Nasal wash cell counts in the presence or absence of oseltamivir treatment.

Anthony C. Marriott (111070)
Brian K. Dove (111063)
Catherine J. Whittaker (548404)
Christine Bruce (548405)
Kathryn A. Ryan (548406)
Thomas J. Bean (548407)
Emma Rayner (534415)
Geoff Pearson (548408)
Irene Taylor (111066)
Stuart Dowall (548409)
Jenna Plank (548410)
Edmund Newman (548411)
Wendy S. Barclay (202288)
Nigel J. Dimmock (111061)
Andrew J. Easton (111072)
Bassam Hallis (111069)
Nigel J. Silman (273502)
Miles W. Carroll (111071)

April 2014

A, prophylactic oseltamivir regimen from 2; B, therapeutic oseltamivir regimen from 6 hr post-inf...

Plasma pharmacokinetic parameters of vincristine in the Tasmanian devil (median data reported corrected for a dose of vincristine 0.05 mg/kg).

David N. Phalen (129542)
Angela Frimberger (419193)
Stephen Pyecroft (309745)
Sarah Peck (419194)
Colette Harmsen (419195)
Suzanneth Lola (419196)
Beatriz de Mello Mattos (419197)
Kong M. Li (307287)
Andrew J. McLachlan (419198)
Antony Moore (419199)

June 2013

Note: AUC(0-∞); area under the concentration time curve extrapolated to infinity after...

Main pharmacokinetic parameters (mean±SD) after oral administration of DAS (25 mg/kg) to rats (n = 5).

Hadir M. Maher (5394977)
Nourah Z. Alzoman (5394980)
Shereen M. Shehata (5394971)
Norah O. Abanmy (5394974)

June 2018

Main pharmacokinetic parameters (mean±SD) after oral administration of DAS (25 mg/kg) to rats (<i...

Pharmacokinetic parameters for phenylbenzamides after 1 mg/kg intravenous injection or 5mg/kg oral dose in Sprague Dawley rats.

Hiral A. Bhagat (5896475)
Sarah A. Compton (5896478)
David L. Musso (3012933)
Christopher P. Laudeman (2425168)
Kimberly M. P. Jackson (5896481)
Na Young Yi (5896484)
Lidia S. Nierobisz (5896487)
Lawrence Forsberg (5896490)
Jay E. Brenman (241583)
Jonathan Z. Sexton (2263105)

October 2018

Pharmacokinetic parameters for phenylbenzamides after 1 mg/kg intravenous injection or 5mg/kg oral d...

Summary of Pharmacokinetic Parameters for Zanamivir from Different Formulations after Intraduodenal Administration in Male Sprague-Dawley Rats at 1.5 mg/animal.

Eric H. Holmes (403612)
Harikrishna Devalapally (403613)
Libin Li (403614)
Michael L. Perdue (403615)
Gary K. Ostrander (403616)

April 2013

Cmax: Maximum plasma concentration; tmax: Time to maximum plasma concentrat...

OC PK parameters estimated in ferrets with and without anesthesia.

Micaela B. Reddy (384270)
Kuo-Hsiung Yang (650738)
Gauri Rao (812523)
Craig R. Rayner (384272)
Jing Nie (139250)
Chandrasena Pamulapati (812524)
Bindumadhav M. Marathe (446548)
Alan Forrest (210305)
Elena A. Govorkova (44419)

October 2015

a The CL and V parameters are conditioned on oral bioavailability and fraction of pare...

Oseltamivir Population Pharmacokinetics in the Ferret: Model Application for Pharmacokinetic/Pharmacodynamic Study Design

Micaela B. Reddy (384270)
Kuo-Hsiung Yang (650738)
Gauri Rao (812523)
Craig R. Rayner (384272)
Jing Nie (139250)
Chandrasena Pamulapati (812524)
Bindumadhav M. Marathe (446548)
Alan Forrest (210305)
Elena A. Govorkova (44419)

October 2015

<div>The ferret is a suitable small animal model for preclinical evaluation of efficacy of antivi...

Oseltamivir Population Pharmacokinetics in the Ferret: Model Application for Pharmacokinetic/Pharmacodynamic Study Design.

Micaela B Reddy
Kuo-Hsiung Yang
Gauri Rao
Craig R Rayner
Jing Nie
Chandrasena Pamulapati
Bindumadhav M Marathe
Alan Forrest
Elena A Govorkova

The ferret is a suitable small animal model for preclinical evaluation of efficacy of antiviral drug...

OP and OC PK parameters in uninfected ferrets following an oral dose of oseltamivir.a

Micaela B. Reddy (384270)
Kuo-Hsiung Yang (650738)
Gauri Rao (812523)
Craig R. Rayner (384272)
Jing Nie (139250)
Chandrasena Pamulapati (812524)
Bindumadhav M. Marathe (446548)
Alan Forrest (210305)
Elena A. Govorkova (44419)

October 2015

a This PK analysis used data from uninfected animals (e.g., from Study 1, uninfected f...

Pharmacokinetic parameters of aniracetam and N-anisoyl-GABA following oral administration of aniracetam to pigeons.

Hannah Phillips (6616406)
Arlene McDowell (6616409)
Birgitte S. Mielby (6616412)
Ian G. Tucker (2382481)
Michael Colombo (27205)

April 2019

Pharmacokinetic parameters of aniracetam and N-anisoyl-GABA following oral administration of anirace...

Verdinexor treatment reduces immune cell infiltration and pro-inflammatory cytokine expression and in influenza-infected ferrets.

Olivia Perwitasari (2742820)
Scott Johnson (150270)
Xiuzhen Yan (166271)
Emery Register (3366842)
Jackelyn Crabtree (425215)
Jon Gabbard (645849)
Elizabeth Howerth (3366836)
Sharon Shacham (519876)
Robert Carlson (2044168)
Sharon Tamir (3366839)
Ralph A. Tripp (166289)

November 2016

Ferrets were i.n. infected with 10×ID50 A/California/04/09 and orally treated with 15 ...

Pharmacokinetic parameters of evocalcet after oral administration to male rats.

Takehisa Kawata (5052257)
Shin Tokunaga (5052263)
Miki Murai (2654710)
Nami Masuda (5052245)
Waka Haruyama (5052260)
Youji Shoukei (5052248)
Yutaka Hisada (5052251)
Tetsuya Yanagida (580156)
Hiroshi Miyazaki (459162)
Michihito Wada (5052254)
Tadao Akizawa (316095)
Masafumi Fukagawa (721664)

April 2018

Pharmacokinetic parameters of evocalcet after oral administration to male rats.</p

OC PK parameters estimated in uninfected and influenza virus-infected ferrets.

Micaela B. Reddy (384270)
Kuo-Hsiung Yang (650738)
Gauri Rao (812523)
Craig R. Rayner (384272)
Jing Nie (139250)
Chandrasena Pamulapati (812524)
Bindumadhav M. Marathe (446548)
Alan Forrest (210305)
Elena A. Govorkova (44419)

October 2015

a The CL and V parameters are conditioned on oral bioavailability and fraction of pare...

Pharmacokinetic parameters determined for a treatment schedule of four applications of diminazene (at 5 mg/kg), DB 75, DB 867 and DB 1192 (at 2.5 mg/kg and 1.25 mg/kg), based on average plasma concentration levels taken from T. evansi experimentally infected goats.

Kirsten Gillingwater (349563)
Carlos Gutierrez (349565)
Arlene Bridges (349566)
Huali Wu (349567)
Stijn Deborggraeve (56957)
Rosine Ali Ekangu (246157)
Arvind Kumar (227201)
Mohamed Ismail (349568)
David Boykin (349569)
Reto Brun (41511)

February 2013

Pharmacokinetic parameters determined for a treatment schedule of four applications of diminazene...

Mean manual activity score of non-infected ferrets and infected ferrets with or without oseltamivir treatment from day 0 to day 11 post-infection.

Ding Yuan Oh (324894)
Ian G. Barr (216006)
Aeron C. Hurt (215989)

March 2015

OST: OseltamivirMean manual activity score of non-infected ferrets and infected ferrets wi...

Nasal wash cell counts in the presence or absence of oseltamivir treatment.

Anthony C. Marriott (111070)
Brian K. Dove (111063)
Catherine J. Whittaker (548404)
Christine Bruce (548405)
Kathryn A. Ryan (548406)
Thomas J. Bean (548407)
Emma Rayner (534415)
Geoff Pearson (548408)
Irene Taylor (111066)
Stuart Dowall (548409)
Jenna Plank (548410)
Edmund Newman (548411)
Wendy S. Barclay (202288)
Nigel J. Dimmock (111061)
Andrew J. Easton (111072)
Bassam Hallis (111069)
Nigel J. Silman (273502)
Miles W. Carroll (111071)

April 2014

A, prophylactic oseltamivir regimen from 2; B, therapeutic oseltamivir regimen from 6 hr post-inf...

Plasma pharmacokinetic parameters of vincristine in the Tasmanian devil (median data reported corrected for a dose of vincristine 0.05 mg/kg).

David N. Phalen (129542)
Angela Frimberger (419193)
Stephen Pyecroft (309745)
Sarah Peck (419194)
Colette Harmsen (419195)
Suzanneth Lola (419196)
Beatriz de Mello Mattos (419197)
Kong M. Li (307287)
Andrew J. McLachlan (419198)
Antony Moore (419199)

June 2013

Note: AUC(0-∞); area under the concentration time curve extrapolated to infinity after...

Main pharmacokinetic parameters (mean±SD) after oral administration of DAS (25 mg/kg) to rats (n = 5).

Hadir M. Maher (5394977)
Nourah Z. Alzoman (5394980)
Shereen M. Shehata (5394971)
Norah O. Abanmy (5394974)

June 2018

Main pharmacokinetic parameters (mean±SD) after oral administration of DAS (25 mg/kg) to rats (<i...

Pharmacokinetic parameters for phenylbenzamides after 1 mg/kg intravenous injection or 5mg/kg oral dose in Sprague Dawley rats.

Hiral A. Bhagat (5896475)
Sarah A. Compton (5896478)
David L. Musso (3012933)
Christopher P. Laudeman (2425168)
Kimberly M. P. Jackson (5896481)
Na Young Yi (5896484)
Lidia S. Nierobisz (5896487)
Lawrence Forsberg (5896490)
Jay E. Brenman (241583)
Jonathan Z. Sexton (2263105)

October 2018

Pharmacokinetic parameters for phenylbenzamides after 1 mg/kg intravenous injection or 5mg/kg oral d...

Summary of Pharmacokinetic Parameters for Zanamivir from Different Formulations after Intraduodenal Administration in Male Sprague-Dawley Rats at 1.5 mg/animal.

Eric H. Holmes (403612)
Harikrishna Devalapally (403613)
Libin Li (403614)
Michael L. Perdue (403615)
Gary K. Ostrander (403616)

April 2013

Cmax: Maximum plasma concentration; tmax: Time to maximum plasma concentrat...

Pharmacokinetic parameters of verdinexor following a <i>per os</i> dose of 5 mg/kg in male ferrets.

Abstract

Extracted data

Pharmacokinetic parameters of verdinexor following a <i>per os</i> dose of 5 mg/kg in male ferrets.

Abstract

Extracted data

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