<p>A-F,E,G) IL-1β was measured by ELISA in supernatants of LPS-primed BMDMs infected for 6 hours with indicated bacterial strains, or D) cell death was measured by LDH release at 6 hours p.i. (MOI 10). Figures are representative of three or more experiments. Shown is mean plus s.d. for triplicate wells. * p<0.05, **p<0.01, ***p<0.001.</p
SummaryInflammasome assembly activates caspase-1 and initiates the inflammatory cell death program p...
<div><p><i>Yersinia pestis</i> causes pneumonic plague, a disease characterized by inflammation, nec...
YopM is one of the six “effector Yops” of the human-pathogenic Yersinia, but its mechanism has not b...
<div><p>Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-neg...
Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative ba...
Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative ba...
Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative ba...
Thesis (Ph.D.)--University of Washington, 2012The host inflammatory response is strikingly delayed d...
<p>Co-IP pulldown in these cells as well as mouse BMDMs indicate YopM interaction with Pyrin, Rsk1, ...
The virulence protein YopM of the plague bacterium Yersinia pestis has different dominant effects in...
YopM, a protein toxin of Yersinia pestis, is necessary for virulence in a mouse model of systemic pl...
The enteropathogenic Yersinia strains are known to downregulate signaling pathways in macrophages by...
Sepsis is not only the leading cause of death in non-coronary intensive care units (ICUs) but also o...
Sepsis is not only the leading cause of death in non-coronary intensive care units (ICUs) but also o...
Dr. Deborah Anderson, Dissertation Supervisor.includes vita[ACCESS RESTRICTED TO THE UNIVERSITY OF M...
SummaryInflammasome assembly activates caspase-1 and initiates the inflammatory cell death program p...
<div><p><i>Yersinia pestis</i> causes pneumonic plague, a disease characterized by inflammation, nec...
YopM is one of the six “effector Yops” of the human-pathogenic Yersinia, but its mechanism has not b...
<div><p>Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-neg...
Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative ba...
Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative ba...
Type III secretion systems (T3SS) are central virulence factors for many pathogenic Gram-negative ba...
Thesis (Ph.D.)--University of Washington, 2012The host inflammatory response is strikingly delayed d...
<p>Co-IP pulldown in these cells as well as mouse BMDMs indicate YopM interaction with Pyrin, Rsk1, ...
The virulence protein YopM of the plague bacterium Yersinia pestis has different dominant effects in...
YopM, a protein toxin of Yersinia pestis, is necessary for virulence in a mouse model of systemic pl...
The enteropathogenic Yersinia strains are known to downregulate signaling pathways in macrophages by...
Sepsis is not only the leading cause of death in non-coronary intensive care units (ICUs) but also o...
Sepsis is not only the leading cause of death in non-coronary intensive care units (ICUs) but also o...
Dr. Deborah Anderson, Dissertation Supervisor.includes vita[ACCESS RESTRICTED TO THE UNIVERSITY OF M...
SummaryInflammasome assembly activates caspase-1 and initiates the inflammatory cell death program p...
<div><p><i>Yersinia pestis</i> causes pneumonic plague, a disease characterized by inflammation, nec...
YopM is one of the six “effector Yops” of the human-pathogenic Yersinia, but its mechanism has not b...