showing that MCL-1 antagonism increased sensitivity to anoikis in MDA-MB-468-2A but not MDA-MB-231-2A cells. Bar graphs depicting the average fraction of apoptotic cells (total Annexin V-positive by flow cytometry) in MDA-MB-468-2A (A) and MDA-MB-231-2A (B) plated as monolayers in culture (normal) or onto PolyHEMA treated plates and harvested at 24Â hours after plating. ANOVA p value, dashes indicate statistically significant groups. Bars indicate statistically significant groups, p value paired t tests. (JPG 409Â kb
Figure S1: (A) Dysregulation score was calculated according to Pathifier [32] for MAPK and JAK/STAT ...
Figure S7. Assessment of dynamic changes in expression of cell cycle regulatory genes. (a) Log2 diff...
Figure S1. Percentage apoptosis induction by obatoclax and/or lapatinib in HCC1954-Par and HCC1954-L...
Characterization of MDA-MB231 and cisplatin-resistant MDA-MB231CisR. MDA-MB231 and cisplatin-resista...
Figure S6: (A) Percentage of sub-G1 population identified using propidium iodide staining and quanti...
Figure S1. MASTL is associated with poor prognosis in breast cancer. The survival of MASTL in breast...
(A/B) Ba/F3 vector cells and cells transformed with pBABE Bcr-Abl were exposed to the indicated inhi...
Functional analysis after treatment with TGFβ1 (10 μg/mL, A, B, n = 5) and respective controls. Live...
Figure S2.The impact of TRAIL and TNF-alpha treatment in SKBR3-Par, -L and the impact of TRAIL in HC...
Viability analysis of U-87 MG cells. Cells were treated with variable concentrations of D11 for the ...
Figure S5. HMLE-vector and HMLE-Snail cells were treated with a dose range of the tested inhibitors,...
Figure S2. MASTL depletion increases G2 arrest and the accumulation of pH 3. a The quantification of...
Evaluating the ability of pepstatin A (PepA) to block GAEL-induced cell death in EOC140 cells. a. EO...
Cell line specific synergistic drug combination effects. Blue 8 × 8 blue matrices show % viability i...
Figure S2. ED and EAD induce cell growth arrest. (A) qRT-PCR of cyclin D1 (CCND1) and cyclin-depende...
Figure S1: (A) Dysregulation score was calculated according to Pathifier [32] for MAPK and JAK/STAT ...
Figure S7. Assessment of dynamic changes in expression of cell cycle regulatory genes. (a) Log2 diff...
Figure S1. Percentage apoptosis induction by obatoclax and/or lapatinib in HCC1954-Par and HCC1954-L...
Characterization of MDA-MB231 and cisplatin-resistant MDA-MB231CisR. MDA-MB231 and cisplatin-resista...
Figure S6: (A) Percentage of sub-G1 population identified using propidium iodide staining and quanti...
Figure S1. MASTL is associated with poor prognosis in breast cancer. The survival of MASTL in breast...
(A/B) Ba/F3 vector cells and cells transformed with pBABE Bcr-Abl were exposed to the indicated inhi...
Functional analysis after treatment with TGFβ1 (10 μg/mL, A, B, n = 5) and respective controls. Live...
Figure S2.The impact of TRAIL and TNF-alpha treatment in SKBR3-Par, -L and the impact of TRAIL in HC...
Viability analysis of U-87 MG cells. Cells were treated with variable concentrations of D11 for the ...
Figure S5. HMLE-vector and HMLE-Snail cells were treated with a dose range of the tested inhibitors,...
Figure S2. MASTL depletion increases G2 arrest and the accumulation of pH 3. a The quantification of...
Evaluating the ability of pepstatin A (PepA) to block GAEL-induced cell death in EOC140 cells. a. EO...
Cell line specific synergistic drug combination effects. Blue 8 × 8 blue matrices show % viability i...
Figure S2. ED and EAD induce cell growth arrest. (A) qRT-PCR of cyclin D1 (CCND1) and cyclin-depende...
Figure S1: (A) Dysregulation score was calculated according to Pathifier [32] for MAPK and JAK/STAT ...
Figure S7. Assessment of dynamic changes in expression of cell cycle regulatory genes. (a) Log2 diff...
Figure S1. Percentage apoptosis induction by obatoclax and/or lapatinib in HCC1954-Par and HCC1954-L...