<p>(A and B) Susceptibility of WT and mutant strains to Zn(II) as assessed by disk diffusion assay. The data are expressed as the diameter of the zone of inhibition (ZOI) as measured in millimeters. The mean and standard error of three independent experiments is shown. Asterisks indicate significance as determined by a Student’s <i>t</i>-test (P<0.05). (C) Model of the contribution of the Rex regulon to Zn(II) resistance.</p
Zn(II) is an essential metal ion in living organisms, playing a wide variety of roles as a structura...
<p>a.) Disc diffusion assay was performed using discs containing 20 μmol diamide. The zone of inhibi...
<p>Tests were performed in duplicate, and both measurements are reported for each organism/antibioti...
<p>The relative contribution of hZnT1, mMt-I or hZnT4 re-expression in <i>ZnT1</i><sup>−/−</sup><i>M...
<p>Wild type (WT, BY4743) cells and isogenic mutants defective for various antioxidant proteins were...
<p>**<i>P</i>≤0.01 versus wild type for the mutant.</p>a<p>The values are mean±SD for three independ...
<p>A) Oxidative stress response of <i>phoB</i><sup>KP</sup> mutant by disc assay. The <i>phoB</i><su...
<p>(A) Initial rates of diferric-transferrin formation at 460 nm are plotted versus concentration of...
<p><b>A</b>: DTNB pre-exposure (0.5 mM, 10 min) by itself had no effect on either OGD-SD propagation...
<p>(<b>A</b>) Schematic representation of the genomic context adjacent to A1S_0143. (<b>B</b>) CP gr...
<p>THP-1 macrophages were incubated with tested complexes <b>1</b>–<b>7</b> (5 µM), ZnCl<sub>2</sub>...
<p>A and D: cell protein concentrations of controls determined by the Lowry-assay. Passage numbers: ...
<p>(A) Cells were challenged with potentially toxic zinc (1 mM), stained with zinquin and fluorescen...
<p>Monomeric apoSOD1 [C6/111A;F50E;G51E] (<b>1</b>) and the mutants [H46/48/120S] (<b>2</b>), [H71/8...
Sensitive measurements of cellular Zn(II) uptake currently rely on quantitating radioactive emissio...
Zn(II) is an essential metal ion in living organisms, playing a wide variety of roles as a structura...
<p>a.) Disc diffusion assay was performed using discs containing 20 μmol diamide. The zone of inhibi...
<p>Tests were performed in duplicate, and both measurements are reported for each organism/antibioti...
<p>The relative contribution of hZnT1, mMt-I or hZnT4 re-expression in <i>ZnT1</i><sup>−/−</sup><i>M...
<p>Wild type (WT, BY4743) cells and isogenic mutants defective for various antioxidant proteins were...
<p>**<i>P</i>≤0.01 versus wild type for the mutant.</p>a<p>The values are mean±SD for three independ...
<p>A) Oxidative stress response of <i>phoB</i><sup>KP</sup> mutant by disc assay. The <i>phoB</i><su...
<p>(A) Initial rates of diferric-transferrin formation at 460 nm are plotted versus concentration of...
<p><b>A</b>: DTNB pre-exposure (0.5 mM, 10 min) by itself had no effect on either OGD-SD propagation...
<p>(<b>A</b>) Schematic representation of the genomic context adjacent to A1S_0143. (<b>B</b>) CP gr...
<p>THP-1 macrophages were incubated with tested complexes <b>1</b>–<b>7</b> (5 µM), ZnCl<sub>2</sub>...
<p>A and D: cell protein concentrations of controls determined by the Lowry-assay. Passage numbers: ...
<p>(A) Cells were challenged with potentially toxic zinc (1 mM), stained with zinquin and fluorescen...
<p>Monomeric apoSOD1 [C6/111A;F50E;G51E] (<b>1</b>) and the mutants [H46/48/120S] (<b>2</b>), [H71/8...
Sensitive measurements of cellular Zn(II) uptake currently rely on quantitating radioactive emissio...
Zn(II) is an essential metal ion in living organisms, playing a wide variety of roles as a structura...
<p>a.) Disc diffusion assay was performed using discs containing 20 μmol diamide. The zone of inhibi...
<p>Tests were performed in duplicate, and both measurements are reported for each organism/antibioti...