Additional file 1: Table S1. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, Symen
Marzi, Carola
Aslibekyan, Stella
Mendelson, Michael M.
Conneely, Karen N.
Tanaka, Toshiko
Colicino, Elena
Waite, Lindsay L.
Joehanes, Roby
Guan, Weihua
Brody, Jennifer A.
Elks, Cathy
Marioni, Riccardo
Jhun, Min A.
Agha, Golareh
Bressler, Jan
Ward-Caviness, Cavin K.
Chen, Brian H.
Huan, Tianxiao
Bakulski, Kelly
Salfati, Elias L.
Fiorito, Giovanni
Wahl, Simone
Schramm, Katharina
Sha, Jin
Hernandez, Dena G.
Just, Allan C.
Smith, Jennifer A.
Sotoodehnia, Nona
Pilling, Luke C.
Pankow, James S.
Tsao, Phil S.
Liu, Chunyu
Zhao, Wei
Guarrera, Simonetta
Michopoulos, Vasiliki J.
Smith, Alicia K.
Peters, Marjolein J.
Melzer, David
Vokonas, Pantel
Fornage, Myriam
Prokisch, Holger
Bis, Joshua C.
Chu, Audrey Y.
Herder, Christian
Grallert, Harald
Yao, Chen
Shah, Sonia
McRae, Allan F.
Lin, Honghuang
Horvath, Steve
Fallin, Daniele
Hofman, Albert
Wareham, Nicholas J.
Wiggins, Kerri L.
Feinberg, Andrew P.
Starr, John M.
Visscher, Peter M.
Murabito, Joanne M.
Kardia, Sharon L. R.
Absher, Devin M.
Binder, Elisabeth B.
Singleton, Andrew B.
Bandinelli, Stefania
Peters, Annette
Waldenberger, Melanie
Matullo, Giuseppe
Schwartz, Joel D.
Demerath, Ellen W.
Uitterlinden, André G.
van Meurs, Joyce B. J.
Franco, Oscar H.
Chen, Yii-Der Ida
Levy, Daniel
Turner, Stephen T.
Deary, Ian J.
Ressler, Kerry J.
Dupuis, Josée
Ferrucci, Luigi
Ong, Ken K.
Assimes, Themistocles L.
Boerwinkle, Eric
Koenig, Wolfgang
Arnett, Donna K.
Baccarelli, Andrea A.
Benjamin, Emilia J.
Dehghan, Abbas

January 2016

BACKGROUND: Chronic low-grade inflammation reflects a subclinical immune response implicated in the ...

Additional file 3: Table S1. of Methylation patterns in serum DNA for early identification of disseminated breast cancer

Martin Widschwendter (184711)
Iona Evans (3429239)
Allison Jones (184670)
Shohreh Ghazali (4777599)
Daniel Reisel (4777605)
Andy Ryan (3340164)
Aleksandra Gentry-Maharaj (205215)
Michal Zikan (184682)
David Cibula (184688)
Johannes Eichner (236560)
Marianna Alunni-Fabbroni (4543465)
Julian Koch (4054624)
Wolfgang Janni (61953)
Tobias Paprotka (4777602)
Timo Wittenberger (4777596)
Usha Menon (205216)
Benjamin Wahl (606649)
Brigitte Rack (61954)
Harri LempiĂ¤inen (4777608)

December 2017

Coordinates and primers used to amplify the identified target regions using bisulfite sequencing. (P...

Additional file 2: Table S8. of Genome-wide DNA methylation analysis of transient neonatal diabetes type 1 patients with mutations in ZFP57

Mads Bak (181535)
Susanne Boonen (3420221)
Christina Dahl (3530879)
Johanne Hahnemann (3530867)
Deborah Mackay (3530870)
Zeynep TĂźmer (3530864)
Karen GrĂ¸nskov (3530876)
I. Temple (3530873)
Per Guldberg (551836)
Niels Tommerup (118532)

April 2016

Hypo- and hypermethylated regions detected in at least 2 patients. Additionally, the following chara...

Additional file 9: Table S8. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Symen Ligthart (701678)
Carola Marzi (236979)
Stella Aslibekyan (123439)
Michael Mendelson (2697424)
Karen Conneely (3448694)
Toshiko Tanaka (174638)
Elena Colicino (3503048)
Lindsay Waite (3503021)
Roby Joehanes (560601)
Weihua Guan (345071)
Jennifer Brody (174723)
Cathy Elks (3503054)
Riccardo Marioni (669892)
Min Jhun (3503015)
Golareh Agha (3503030)
Jan Bressler (248795)
Cavin Ward-Caviness (3503057)
Brian Chen (149932)
Tianxiao Huan (599733)
Kelly Bakulski (3503063)
Elias Salfati (3503045)
Giovanni Fiorito (136942)
Simone Wahl (112749)
Katharina Schramm (528479)
Jin Sha (847984)
Dena Hernandez (215322)
Allan Just (3448679)
Jennifer Smith (172056)
Nona Sotoodehnia (143373)
Luke Pilling (3503024)
James Pankow (160621)
Phil Tsao (3503066)
Chunyu Liu (9855)
Wei Zhao (14321)
Simonetta Guarrera (136940)
Vasiliki Michopoulos (3503051)
Alicia Smith (3448658)
Marjolein Peters (3503033)
David Melzer (202058)
Pantel Vokonas (587472)
Myriam Fornage (45591)
Holger Prokisch (26590)
Joshua Bis (711982)
Audrey Chu (3503069)
Christian Herder (44905)
Harald Grallert (72666)
Chen Yao (137375)
Sonia Shah (142603)
Allan McRae (3400103)
Honghuang Lin (560598)
Steve Horvath (28847)
Daniele Fallin (3503039)
Albert Hofman (107303)
Nicholas Wareham (153226)
Kerri Wiggins (3503018)
Andrew Feinberg (242567)
John Starr (231855)
Peter Visscher (3400094)
Joanne Murabito (3503036)
Sharon Kardia (3503060)
Devin Absher (217357)
Elisabeth Binder (3448661)
Andrew Singleton (23294)
Stefania Bandinelli (150002)
Annette Peters (62601)
Melanie Waldenberger (236985)
Giuseppe Matullo (136983)
Joel Schwartz (18324)
Ellen Demerath (198657)
AndrĂŠ Uitterlinden (3404267)
Joyce van Meurs (3404240)
Oscar Franco (2885594)
Yii-Der Chen (3503075)
Daniel Levy (51573)
Stephen Turner (3503027)
Ian Deary (489588)
Kerry Ressler (3503072)
JosĂŠe Dupuis (3503084)
Luigi Ferrucci (150038)
Ken Ong (448067)
Themistocles Assimes (746456)
Eric Boerwinkle (36288)
Wolfgang Koenig (26222)
Donna Arnett (192289)
Andrea Baccarelli (36523)
Emelia Benjamin (3503042)
Abbas Dehghan (174878)

December 2016

Significant methylation-expression results and corresponding expression-CRP results for the replicat...

Additional file 2 of Multi–omic analysis of signalling factors in inflammatory comorbidities

Hui Xiao (185054)
Krzysztof Bartoszek (3316341)
Pietro Lio’ (3408941)

November 2018

DNA methylation and gene expression datasets of inflammation related diseases in Step 2. The table i...

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, Symen
Marzi, C. (Carola)
Aslibekyan, S. (Stella)
Mendelson, M.M. (Michael M.)
Conneely, Karen N.
Tanaka, Toshiko
Colicino, E. (Elena)
Waite, Lindsay
Joehanes, Roby
Guan, Weihua
Brody, Jennifer A.
Elks, Cathy
Marioni, Riccardo
Jhun, Min A.
Agha, G. (Golareh)
Bressler, Jan
Ward-Caviness, Cavin K.
Chen, Brian
Huan, Tianxiao
Bakulski, Kelly M.
Salfati, Elias
Fiorito, G. (Giovanni)
Wahl, Simone
Schramm, Katharina
Sha, J. (Jin)
Hernandez, Dena
Just, A.C. (Allan C.)
Smith, Jennifer A
Sotoodehnia, Nona
Pilling, Luke
Pankow, James
Tsao, P.S. (Phil S.)
Liu, C. (Chunyu)
Zhao, Wei
Guarrera, Simonetta
Michopoulos, V.J. (Vasiliki J.)
Smith, A.K. (Alicia K.)
Peters, Marjolein
Melzer, David
Vokonas, P. (Pantel)
Fornage, Myriam
Prokisch, Holger
Bis, Joshua
Chu, Audrey
Herder, Christian
Grallert, Harald
Yao, Chen
Shah, Sonia
McRae, Allan F.
Lin, H.
Horvath, Steve
Fallin, D. (Daniele)
Hofman, Albert
Wareham, Nick
Wiggins, Kerri
Feinberg, Andrew P.
Starr, John
Visscher, Peter
Murabito, Joanne
Kardia, S.L.R. (Sharon L.R.)
Absher, Devin
Binder, Elisabeth
Singleton, Andrew
Bandinelli, Stefania
Peters, Annette
Waldenberger, Melanie
Matullo, G.
Schwartz, J.D. (Joel D.)
Demerath, Ellen
Uitterlinden, André
Meurs, J.B.J. (Joyce B.J.)
Franco, Oscar
Chen, Y.
Levy, Daniel
Turner, Stephen
Deary, Ian
Ressler, Kerry
Dupuis, Josée
Ferrucci, Luigi
Ong, K.K. (Ken K.)
Assimes, Themistocles
Boerwinkle, Eric
Koenig, Wolfgang
Arnett, Donna
Baccarelli, Andrea
Benjamin, Emelia
Dehghan, Abbas

December 2016

Background: Chronic low-grade inflammation reflects a subclinical immune response implicated in the ...

Additional file 1: Table S1. of Assessment of global DNA methylation in peripheral blood cell subpopulations of early rheumatoid arthritis before and after methotrexate

MarĂa de Andres (3553853)
Eva Perez-Pampin (63804)
Manuel Calaza (134680)
Francisco Santaclara (3553859)
Ignacio Ortea (2340007)
Juan Gomez-Reino (3553856)
Antonio Gonzalez (2150521)

August 2015

Primers used for assessing the expression level of methylation-relevant enzymes by qPCR. (DOC 36 kb

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, Symen
Marzi, Carola
Aslibekyan, Stella
Mendelson, Michael M.
Conneely, Karen N.
Tanaka, Toshiko
Colicino, Elena
Waite, Lindsay L.
Joehanes, Roby
Guan, Weihua
Brody, Jennifer A.
Elks, Cathy
Marioni, Riccardo
Jhun, Min A.
Agha, Golareh
Bressler, Jan
Ward-Caviness, Cavin K.
Chen, Brian H.
Huan, Tianxiao
Bakulski, Kelly
Salfati, Elias L.
Fiorito, Giovanni
Wahl, Simone
Schramm, Katharina
Sha, Jin
Hernandez, Dena G.
Just, Allan C.
Smith, Jennifer A.
Sotoodehnia, Nona
Pilling, Luke C.
Pankow, James S.

December 2016

Chronic low-grade inflammation reflects a subclinical immune response implicated in the pathogenesis...

Additional file 4: Table S4. of Genome-wide DNA methylation profile identified a unique set of differentially methylated immune genes in oral squamous cell carcinoma patients in India

Baidehi Basu (3717586)
Joyeeta Chakraborty (3717592)
Aditi Chandra (3717583)
Atul Katarkar (282856)
Jadav Baldevbhai (3717589)
Debjit Dhar Chowdhury (3717580)
Jay Ray (3717595)
Keya Chaudhuri (90539)
Raghunath Chatterjee (90538)

February 2017

Spreadsheet showing list of all unique differentially methylated probes. (XLSX 23 kb

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, S. (Symen)
Marzi, C. (Carola)
Aslibekyan, S. (Stella)
Mendelson, M.M. (Michael M.)
Conneely, K.N. (Karen N.)
Tanaka, T. (Toshiko)
Colicino, E. (Elena)
Waite, L. (Lindsay)
Joehanes, R. (Roby)
Guan, W. (Weihua)
Brody, J.A. (Jennifer A.)
Elks, C.E. (Cathy)
Marioni, R.E. (Riccardo)
Jhun, M.A. (Min A.)
Agha, G. (Golareh)
Bressler, J. (Jan)
Ward-Caviness, C.K. (Cavin K.)
Chen, B.H. (Brian)
Huan, T. (Tianxiao)
Bakulski, K.M. (Kelly M.)
Salfati, E. (Elias)
Fiorito, G. (Giovanni)
Wahl, S. (Simone)
Schramm, K. (Katharina)
Sha, J. (Jin)
Hernandez, D.G. (Dena)
Just, A.C. (Allan C.)
Smith, J.A. (Jennifer A)
Sotoodehnia, N. (Nona)
Pilling, L.C. (Luke)
Pankow, J.S. (James)
Tsao, P.S. (Phil S.)
Liu, C. (Chunyu)
Zhao, W. (Wei)
Guarrera, S. (Simonetta)
Michopoulos, V.J. (Vasiliki J.)
Smith, A.K. (Alicia K.)
Peters, M.J. (Marjolein)
Melzer, D. (David)
Vokonas, P. (Pantel)
Fornage, M. (Myriam)
Prokisch, H. (Holger)
Bis, J.C. (Joshua)
Chu, A.Y. (Audrey)
Herder, C. (Christian)
Grallert, H. (Harald)
Yao, C. (Chen)
Shah, S. (Sonia)
McRae, A.F. (Allan F.)
Lin, H.
Horvath, S. (Steve)
Fallin, D. (Daniele)
Hofman, A. (Albert)
Wareham, N.J. (Nick)
Wiggins, K.L. (Kerri)
Feinberg, A.P. (Andrew P.)
Starr, J.M. (John)
Visscher, P.M. (Peter)
Murabito, J. (Joanne)
Kardia, S.L.R. (Sharon L.R.)
Absher, D. (Devin)
Binder, E.B. (Elisabeth)
Singleton, A. (Andrew)
Bandinelli, S. (Stefania)
Peters, A. (Annette)
Waldenberger, M. (Melanie)
Matullo, G.
Schwartz, J.D. (Joel D.)
Demerath, E.W. (Ellen)
Uitterlinden, A.G. (André)
Meurs, J.B.J. (Joyce B.J.)
Franco, O.H. (Oscar)
Chen, Y.D. (Y.)
Levy, D. (Daniel)
Turner, S.T. (Stephen)
Deary, I.J. (Ian)
Ressler, K.J. (Kerry)
Dupuis, J. (Josée)
Ferrucci, L. (Luigi)
Ong, K.K. (Ken K.)
Assimes, T.L. (Themistocles)
Boerwinkle, E.A. (Eric)
Koenig, W. (Wolfgang)
Arnett, D.K. (Donna)
Baccarelli, A.A. (Andrea)
Benjamin, E.J. (Emelia)
Dehghan, A. (Abbas)

December 2016

Background: Chronic low-grade inflammation reflects a subclinical immune response implicated in the ...

Additional file 1: of ZBTB12 DNA methylation is associated with coagulation- and inflammation-related blood cell parameters: findings from the Moli-family cohort

Fabrizia Noro (6691304)
Francesco Gianfagna (440763)
Alessandro Gialluisi (3413885)
Amalia Curtis (6691307)
Augusto Castelnuovo (6691310)
Emanuela Napoleone (6691313)
Chiara Cerletti (285583)
Maria Donati (6691316)
Giovanni Gaetano (6691319)
Marc Hoylaerts (187742)
Licia Iacoviello (285585)
Benedetta Izzi (160858)

May 2019

Putative transcription factor (TF) binding analysis of the blood cell count specific CpG units. Tran...

Additional file 2: of Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

Anna Stevenson (5795498)
Daniel McCartney (3464459)
Sarah Harris (4064788)
Adele Taylor (677047)
Paul Redmond (107693)
John Starr (231855)
Qian Zhang (49333)
Allan McRae (3400103)
Naomi Wray (3449882)
Tara Spires-Jones (6109643)
Barry McColl (6109646)
Andrew McIntosh (83234)
Ian Deary (489588)
Riccardo Marioni (669892)

December 2018

LBC1936 DNA Methylation. DNA methylation profiling methods of LBC1936. (DOCX 17.9 kb

Additional file 1: Tables S1. of Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

Matthew Machin (3848722)
André Amaral (3848719)
Matthias Wielscher (3848728)
Faisal Rezwan (3848725)
Medea Imboden (110145)
Marjo-Riitta Jarvelin (110290)
Ian Adcock (486486)
Nicole Probst-Hensch (520032)
John Holloway (2159533)
Deborah Jarvis (59834)

March 2017

Search terms (n = 92) used within MEDLINE, EMBASE and Web of Science. (DOCX 13 kb

Additional file 1: of Genome-wide DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine

Zachary Gerring (4787301)
Allan McRae (3400103)
Grant Montgomery (16569)
Dale Nyholt (4787298)

January 2018

Differentially methylated regions identified by a sliding window analysis. This file contains the ge...

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.

Ligthart, S.
Marzi, C.
Aslibekyan, S.
Mendelson, M.M.
Conneely, K.N.
Tanaka, T.
Colicino, E.
Waite, L.L.
Joehanes, R.
Guan, W.
Brody, J.A.
Elks, C.E.
Marioni, R.E.
Jhun, M.A.
Agha, G.
Bressler, J.
Ward-Caviness, C.K.
Chen, B.H.
Huan, T.
Bakulski, K.
Salfati, E.L.
Fiorito, G.
Wahl, S.
Schramm, K.
Sha, J.
Hernandez, D.G.
Just, A.C.
Smith, J.A.
Sotoodehnia, N.
Pilling, L.C.
Pankow, J.S.
Tsao, P.S.
Liu, C.
Zhao, W.
Guarrera, S.
Michopoulos, V.J.
Smith, A.K.
Peters, M.J.
Melzer, D.
Vokonas, P.
Fornage, M.
Prokisch, H.
Bis, J.C.
Chu, A.Y.
Herder, C.
Grallert, H.
Yao, C.
Shah, S.
McRae, A.F.
Lin, H.
Horvath, S.
Fallin, D.
Hofman, A.
Wareham, N.J.
Wiggins, K.L.
Feinberg, A.P.
Starr, J.M.
Visscher, P.M.
Murabito, J.M.
Kardia, S.L.R.
Absher, D.M.
Binder, E.B.
Singleton, A.B.
Bandinelli, S.
Peters, A.
Waldenberger, M.
Matullo, G.
Schwartz, J.D.
Demerath, E.W.
Uitterlinden, A.G.
Meurs, J.B.J.
Franco, O.H.
Chen, Y.D.I.
Levy, D.
Turner, S.T.
Deary, I.J.

January 2016

Background: Chronic low-grade inflammation reflects a subclinical immune response implicated in the ...

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, Symen
Marzi, Carola
Aslibekyan, Stella
Mendelson, Michael M.
Conneely, Karen N.
Tanaka, Toshiko
Colicino, Elena
Waite, Lindsay L.
Joehanes, Roby
Guan, Weihua
Brody, Jennifer A.
Elks, Cathy
Marioni, Riccardo
Jhun, Min A.
Agha, Golareh
Bressler, Jan
Ward-Caviness, Cavin K.
Chen, Brian H.
Huan, Tianxiao
Bakulski, Kelly
Salfati, Elias L.
Fiorito, Giovanni
Wahl, Simone
Schramm, Katharina
Sha, Jin
Hernandez, Dena G.
Just, Allan C.
Smith, Jennifer A.
Sotoodehnia, Nona
Pilling, Luke C.
Pankow, James S.
Tsao, Phil S.
Liu, Chunyu
Zhao, Wei
Guarrera, Simonetta
Michopoulos, Vasiliki J.
Smith, Alicia K.
Peters, Marjolein J.
Melzer, David
Vokonas, Pantel
Fornage, Myriam
Prokisch, Holger
Bis, Joshua C.
Chu, Audrey Y.
Herder, Christian
Grallert, Harald
Yao, Chen
Shah, Sonia
McRae, Allan F.
Lin, Honghuang
Horvath, Steve
Fallin, Daniele
Hofman, Albert
Wareham, Nicholas J.
Wiggins, Kerri L.
Feinberg, Andrew P.
Starr, John M.
Visscher, Peter M.
Murabito, Joanne M.
Kardia, Sharon L. R.
Absher, Devin M.
Binder, Elisabeth B.
Singleton, Andrew B.
Bandinelli, Stefania
Peters, Annette
Waldenberger, Melanie
Matullo, Giuseppe
Schwartz, Joel D.
Demerath, Ellen W.
Uitterlinden, André G.
van Meurs, Joyce B. J.
Franco, Oscar H.
Chen, Yii-Der Ida
Levy, Daniel
Turner, Stephen T.
Deary, Ian J.
Ressler, Kerry J.
Dupuis, Josée
Ferrucci, Luigi
Ong, Ken K.
Assimes, Themistocles L.
Boerwinkle, Eric
Koenig, Wolfgang
Arnett, Donna K.
Baccarelli, Andrea A.
Benjamin, Emilia J.
Dehghan, Abbas

January 2016

BACKGROUND: Chronic low-grade inflammation reflects a subclinical immune response implicated in the ...

Additional file 3: Table S1. of Methylation patterns in serum DNA for early identification of disseminated breast cancer

Martin Widschwendter (184711)
Iona Evans (3429239)
Allison Jones (184670)
Shohreh Ghazali (4777599)
Daniel Reisel (4777605)
Andy Ryan (3340164)
Aleksandra Gentry-Maharaj (205215)
Michal Zikan (184682)
David Cibula (184688)
Johannes Eichner (236560)
Marianna Alunni-Fabbroni (4543465)
Julian Koch (4054624)
Wolfgang Janni (61953)
Tobias Paprotka (4777602)
Timo Wittenberger (4777596)
Usha Menon (205216)
Benjamin Wahl (606649)
Brigitte Rack (61954)
Harri LempiĂ¤inen (4777608)

December 2017

Coordinates and primers used to amplify the identified target regions using bisulfite sequencing. (P...

Additional file 2: Table S8. of Genome-wide DNA methylation analysis of transient neonatal diabetes type 1 patients with mutations in ZFP57

Mads Bak (181535)
Susanne Boonen (3420221)
Christina Dahl (3530879)
Johanne Hahnemann (3530867)
Deborah Mackay (3530870)
Zeynep TĂźmer (3530864)
Karen GrĂ¸nskov (3530876)
I. Temple (3530873)
Per Guldberg (551836)
Niels Tommerup (118532)

April 2016

Hypo- and hypermethylated regions detected in at least 2 patients. Additionally, the following chara...

Additional file 9: Table S8. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Symen Ligthart (701678)
Carola Marzi (236979)
Stella Aslibekyan (123439)
Michael Mendelson (2697424)
Karen Conneely (3448694)
Toshiko Tanaka (174638)
Elena Colicino (3503048)
Lindsay Waite (3503021)
Roby Joehanes (560601)
Weihua Guan (345071)
Jennifer Brody (174723)
Cathy Elks (3503054)
Riccardo Marioni (669892)
Min Jhun (3503015)
Golareh Agha (3503030)
Jan Bressler (248795)
Cavin Ward-Caviness (3503057)
Brian Chen (149932)
Tianxiao Huan (599733)
Kelly Bakulski (3503063)
Elias Salfati (3503045)
Giovanni Fiorito (136942)
Simone Wahl (112749)
Katharina Schramm (528479)
Jin Sha (847984)
Dena Hernandez (215322)
Allan Just (3448679)
Jennifer Smith (172056)
Nona Sotoodehnia (143373)
Luke Pilling (3503024)
James Pankow (160621)
Phil Tsao (3503066)
Chunyu Liu (9855)
Wei Zhao (14321)
Simonetta Guarrera (136940)
Vasiliki Michopoulos (3503051)
Alicia Smith (3448658)
Marjolein Peters (3503033)
David Melzer (202058)
Pantel Vokonas (587472)
Myriam Fornage (45591)
Holger Prokisch (26590)
Joshua Bis (711982)
Audrey Chu (3503069)
Christian Herder (44905)
Harald Grallert (72666)
Chen Yao (137375)
Sonia Shah (142603)
Allan McRae (3400103)
Honghuang Lin (560598)
Steve Horvath (28847)
Daniele Fallin (3503039)
Albert Hofman (107303)
Nicholas Wareham (153226)
Kerri Wiggins (3503018)
Andrew Feinberg (242567)
John Starr (231855)
Peter Visscher (3400094)
Joanne Murabito (3503036)
Sharon Kardia (3503060)
Devin Absher (217357)
Elisabeth Binder (3448661)
Andrew Singleton (23294)
Stefania Bandinelli (150002)
Annette Peters (62601)
Melanie Waldenberger (236985)
Giuseppe Matullo (136983)
Joel Schwartz (18324)
Ellen Demerath (198657)
AndrĂŠ Uitterlinden (3404267)
Joyce van Meurs (3404240)
Oscar Franco (2885594)
Yii-Der Chen (3503075)
Daniel Levy (51573)
Stephen Turner (3503027)
Ian Deary (489588)
Kerry Ressler (3503072)
JosĂŠe Dupuis (3503084)
Luigi Ferrucci (150038)
Ken Ong (448067)
Themistocles Assimes (746456)
Eric Boerwinkle (36288)
Wolfgang Koenig (26222)
Donna Arnett (192289)
Andrea Baccarelli (36523)
Emelia Benjamin (3503042)
Abbas Dehghan (174878)

December 2016

Significant methylation-expression results and corresponding expression-CRP results for the replicat...

Additional file 2 of Multi–omic analysis of signalling factors in inflammatory comorbidities

Hui Xiao (185054)
Krzysztof Bartoszek (3316341)
Pietro Lio’ (3408941)

November 2018

DNA methylation and gene expression datasets of inflammation related diseases in Step 2. The table i...

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, Symen
Marzi, C. (Carola)
Aslibekyan, S. (Stella)
Mendelson, M.M. (Michael M.)
Conneely, Karen N.
Tanaka, Toshiko
Colicino, E. (Elena)
Waite, Lindsay
Joehanes, Roby
Guan, Weihua
Brody, Jennifer A.
Elks, Cathy
Marioni, Riccardo
Jhun, Min A.
Agha, G. (Golareh)
Bressler, Jan
Ward-Caviness, Cavin K.
Chen, Brian
Huan, Tianxiao
Bakulski, Kelly M.
Salfati, Elias
Fiorito, G. (Giovanni)
Wahl, Simone
Schramm, Katharina
Sha, J. (Jin)
Hernandez, Dena
Just, A.C. (Allan C.)
Smith, Jennifer A
Sotoodehnia, Nona
Pilling, Luke
Pankow, James
Tsao, P.S. (Phil S.)
Liu, C. (Chunyu)
Zhao, Wei
Guarrera, Simonetta
Michopoulos, V.J. (Vasiliki J.)
Smith, A.K. (Alicia K.)
Peters, Marjolein
Melzer, David
Vokonas, P. (Pantel)
Fornage, Myriam
Prokisch, Holger
Bis, Joshua
Chu, Audrey
Herder, Christian
Grallert, Harald
Yao, Chen
Shah, Sonia
McRae, Allan F.
Lin, H.
Horvath, Steve
Fallin, D. (Daniele)
Hofman, Albert
Wareham, Nick
Wiggins, Kerri
Feinberg, Andrew P.
Starr, John
Visscher, Peter
Murabito, Joanne
Kardia, S.L.R. (Sharon L.R.)
Absher, Devin
Binder, Elisabeth
Singleton, Andrew
Bandinelli, Stefania
Peters, Annette
Waldenberger, Melanie
Matullo, G.
Schwartz, J.D. (Joel D.)
Demerath, Ellen
Uitterlinden, André
Meurs, J.B.J. (Joyce B.J.)
Franco, Oscar
Chen, Y.
Levy, Daniel
Turner, Stephen
Deary, Ian
Ressler, Kerry
Dupuis, Josée
Ferrucci, Luigi
Ong, K.K. (Ken K.)
Assimes, Themistocles
Boerwinkle, Eric
Koenig, Wolfgang
Arnett, Donna
Baccarelli, Andrea
Benjamin, Emelia
Dehghan, Abbas

December 2016

Background: Chronic low-grade inflammation reflects a subclinical immune response implicated in the ...

Additional file 1: Table S1. of Assessment of global DNA methylation in peripheral blood cell subpopulations of early rheumatoid arthritis before and after methotrexate

MarĂa de Andres (3553853)
Eva Perez-Pampin (63804)
Manuel Calaza (134680)
Francisco Santaclara (3553859)
Ignacio Ortea (2340007)
Juan Gomez-Reino (3553856)
Antonio Gonzalez (2150521)

August 2015

Primers used for assessing the expression level of methylation-relevant enzymes by qPCR. (DOC 36 kb

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, Symen
Marzi, Carola
Aslibekyan, Stella
Mendelson, Michael M.
Conneely, Karen N.
Tanaka, Toshiko
Colicino, Elena
Waite, Lindsay L.
Joehanes, Roby
Guan, Weihua
Brody, Jennifer A.
Elks, Cathy
Marioni, Riccardo
Jhun, Min A.
Agha, Golareh
Bressler, Jan
Ward-Caviness, Cavin K.
Chen, Brian H.
Huan, Tianxiao
Bakulski, Kelly
Salfati, Elias L.
Fiorito, Giovanni
Wahl, Simone
Schramm, Katharina
Sha, Jin
Hernandez, Dena G.
Just, Allan C.
Smith, Jennifer A.
Sotoodehnia, Nona
Pilling, Luke C.
Pankow, James S.

December 2016

Chronic low-grade inflammation reflects a subclinical immune response implicated in the pathogenesis...

Additional file 4: Table S4. of Genome-wide DNA methylation profile identified a unique set of differentially methylated immune genes in oral squamous cell carcinoma patients in India

Baidehi Basu (3717586)
Joyeeta Chakraborty (3717592)
Aditi Chandra (3717583)
Atul Katarkar (282856)
Jadav Baldevbhai (3717589)
Debjit Dhar Chowdhury (3717580)
Jay Ray (3717595)
Keya Chaudhuri (90539)
Raghunath Chatterjee (90538)

February 2017

Spreadsheet showing list of all unique differentially methylated probes. (XLSX 23 kb

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, S. (Symen)
Marzi, C. (Carola)
Aslibekyan, S. (Stella)
Mendelson, M.M. (Michael M.)
Conneely, K.N. (Karen N.)
Tanaka, T. (Toshiko)
Colicino, E. (Elena)
Waite, L. (Lindsay)
Joehanes, R. (Roby)
Guan, W. (Weihua)
Brody, J.A. (Jennifer A.)
Elks, C.E. (Cathy)
Marioni, R.E. (Riccardo)
Jhun, M.A. (Min A.)
Agha, G. (Golareh)
Bressler, J. (Jan)
Ward-Caviness, C.K. (Cavin K.)
Chen, B.H. (Brian)
Huan, T. (Tianxiao)
Bakulski, K.M. (Kelly M.)
Salfati, E. (Elias)
Fiorito, G. (Giovanni)
Wahl, S. (Simone)
Schramm, K. (Katharina)
Sha, J. (Jin)
Hernandez, D.G. (Dena)
Just, A.C. (Allan C.)
Smith, J.A. (Jennifer A)
Sotoodehnia, N. (Nona)
Pilling, L.C. (Luke)
Pankow, J.S. (James)
Tsao, P.S. (Phil S.)
Liu, C. (Chunyu)
Zhao, W. (Wei)
Guarrera, S. (Simonetta)
Michopoulos, V.J. (Vasiliki J.)
Smith, A.K. (Alicia K.)
Peters, M.J. (Marjolein)
Melzer, D. (David)
Vokonas, P. (Pantel)
Fornage, M. (Myriam)
Prokisch, H. (Holger)
Bis, J.C. (Joshua)
Chu, A.Y. (Audrey)
Herder, C. (Christian)
Grallert, H. (Harald)
Yao, C. (Chen)
Shah, S. (Sonia)
McRae, A.F. (Allan F.)
Lin, H.
Horvath, S. (Steve)
Fallin, D. (Daniele)
Hofman, A. (Albert)
Wareham, N.J. (Nick)
Wiggins, K.L. (Kerri)
Feinberg, A.P. (Andrew P.)
Starr, J.M. (John)
Visscher, P.M. (Peter)
Murabito, J. (Joanne)
Kardia, S.L.R. (Sharon L.R.)
Absher, D. (Devin)
Binder, E.B. (Elisabeth)
Singleton, A. (Andrew)
Bandinelli, S. (Stefania)
Peters, A. (Annette)
Waldenberger, M. (Melanie)
Matullo, G.
Schwartz, J.D. (Joel D.)
Demerath, E.W. (Ellen)
Uitterlinden, A.G. (André)
Meurs, J.B.J. (Joyce B.J.)
Franco, O.H. (Oscar)
Chen, Y.D. (Y.)
Levy, D. (Daniel)
Turner, S.T. (Stephen)
Deary, I.J. (Ian)
Ressler, K.J. (Kerry)
Dupuis, J. (Josée)
Ferrucci, L. (Luigi)
Ong, K.K. (Ken K.)
Assimes, T.L. (Themistocles)
Boerwinkle, E.A. (Eric)
Koenig, W. (Wolfgang)
Arnett, D.K. (Donna)
Baccarelli, A.A. (Andrea)
Benjamin, E.J. (Emelia)
Dehghan, A. (Abbas)

December 2016

Background: Chronic low-grade inflammation reflects a subclinical immune response implicated in the ...

Additional file 1: of ZBTB12 DNA methylation is associated with coagulation- and inflammation-related blood cell parameters: findings from the Moli-family cohort

Fabrizia Noro (6691304)
Francesco Gianfagna (440763)
Alessandro Gialluisi (3413885)
Amalia Curtis (6691307)
Augusto Castelnuovo (6691310)
Emanuela Napoleone (6691313)
Chiara Cerletti (285583)
Maria Donati (6691316)
Giovanni Gaetano (6691319)
Marc Hoylaerts (187742)
Licia Iacoviello (285585)
Benedetta Izzi (160858)

May 2019

Putative transcription factor (TF) binding analysis of the blood cell count specific CpG units. Tran...

Additional file 2: of Trajectories of inflammatory biomarkers over the eighth decade and their associations with immune cell profiles and epigenetic ageing

Anna Stevenson (5795498)
Daniel McCartney (3464459)
Sarah Harris (4064788)
Adele Taylor (677047)
Paul Redmond (107693)
John Starr (231855)
Qian Zhang (49333)
Allan McRae (3400103)
Naomi Wray (3449882)
Tara Spires-Jones (6109643)
Barry McColl (6109646)
Andrew McIntosh (83234)
Ian Deary (489588)
Riccardo Marioni (669892)

December 2018

LBC1936 DNA Methylation. DNA methylation profiling methods of LBC1936. (DOCX 17.9 kb

Additional file 1: Tables S1. of Systematic review of lung function and COPD with peripheral blood DNA methylation in population based studies

Matthew Machin (3848722)
André Amaral (3848719)
Matthias Wielscher (3848728)
Faisal Rezwan (3848725)
Medea Imboden (110145)
Marjo-Riitta Jarvelin (110290)
Ian Adcock (486486)
Nicole Probst-Hensch (520032)
John Holloway (2159533)
Deborah Jarvis (59834)

March 2017

Search terms (n = 92) used within MEDLINE, EMBASE and Web of Science. (DOCX 13 kb

Additional file 1: of Genome-wide DNA methylation profiling in whole blood reveals epigenetic signatures associated with migraine

Zachary Gerring (4787301)
Allan McRae (3400103)
Grant Montgomery (16569)
Dale Nyholt (4787298)

January 2018

Differentially methylated regions identified by a sliding window analysis. This file contains the ge...

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases.

Ligthart, S.
Marzi, C.
Aslibekyan, S.
Mendelson, M.M.
Conneely, K.N.
Tanaka, T.
Colicino, E.
Waite, L.L.
Joehanes, R.
Guan, W.
Brody, J.A.
Elks, C.E.
Marioni, R.E.
Jhun, M.A.
Agha, G.
Bressler, J.
Ward-Caviness, C.K.
Chen, B.H.
Huan, T.
Bakulski, K.
Salfati, E.L.
Fiorito, G.
Wahl, S.
Schramm, K.
Sha, J.
Hernandez, D.G.
Just, A.C.
Smith, J.A.
Sotoodehnia, N.
Pilling, L.C.
Pankow, J.S.
Tsao, P.S.
Liu, C.
Zhao, W.
Guarrera, S.
Michopoulos, V.J.
Smith, A.K.
Peters, M.J.
Melzer, D.
Vokonas, P.
Fornage, M.
Prokisch, H.
Bis, J.C.
Chu, A.Y.
Herder, C.
Grallert, H.
Yao, C.
Shah, S.
McRae, A.F.
Lin, H.
Horvath, S.
Fallin, D.
Hofman, A.
Wareham, N.J.
Wiggins, K.L.
Feinberg, A.P.
Starr, J.M.
Visscher, P.M.
Murabito, J.M.
Kardia, S.L.R.
Absher, D.M.
Binder, E.B.
Singleton, A.B.
Bandinelli, S.
Peters, A.
Waldenberger, M.
Matullo, G.
Schwartz, J.D.
Demerath, E.W.
Uitterlinden, A.G.
Meurs, J.B.J.
Franco, O.H.
Chen, Y.D.I.
Levy, D.
Turner, S.T.
Deary, I.J.

January 2016

Background: Chronic low-grade inflammation reflects a subclinical immune response implicated in the ...

DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Ligthart, Symen
Marzi, Carola
Aslibekyan, Stella
Mendelson, Michael M.
Conneely, Karen N.
Tanaka, Toshiko
Colicino, Elena
Waite, Lindsay L.
Joehanes, Roby
Guan, Weihua
Brody, Jennifer A.
Elks, Cathy
Marioni, Riccardo
Jhun, Min A.
Agha, Golareh
Bressler, Jan
Ward-Caviness, Cavin K.
Chen, Brian H.
Huan, Tianxiao
Bakulski, Kelly
Salfati, Elias L.
Fiorito, Giovanni
Wahl, Simone
Schramm, Katharina
Sha, Jin
Hernandez, Dena G.
Just, Allan C.
Smith, Jennifer A.
Sotoodehnia, Nona
Pilling, Luke C.
Pankow, James S.
Tsao, Phil S.
Liu, Chunyu
Zhao, Wei
Guarrera, Simonetta
Michopoulos, Vasiliki J.
Smith, Alicia K.
Peters, Marjolein J.
Melzer, David
Vokonas, Pantel
Fornage, Myriam
Prokisch, Holger
Bis, Joshua C.
Chu, Audrey Y.
Herder, Christian
Grallert, Harald
Yao, Chen
Shah, Sonia
McRae, Allan F.
Lin, Honghuang
Horvath, Steve
Fallin, Daniele
Hofman, Albert
Wareham, Nicholas J.
Wiggins, Kerri L.
Feinberg, Andrew P.
Starr, John M.
Visscher, Peter M.
Murabito, Joanne M.
Kardia, Sharon L. R.
Absher, Devin M.
Binder, Elisabeth B.
Singleton, Andrew B.
Bandinelli, Stefania
Peters, Annette
Waldenberger, Melanie
Matullo, Giuseppe
Schwartz, Joel D.
Demerath, Ellen W.
Uitterlinden, André G.
van Meurs, Joyce B. J.
Franco, Oscar H.
Chen, Yii-Der Ida
Levy, Daniel
Turner, Stephen T.
Deary, Ian J.
Ressler, Kerry J.
Dupuis, Josée
Ferrucci, Luigi
Ong, Ken K.
Assimes, Themistocles L.
Boerwinkle, Eric
Koenig, Wolfgang
Arnett, Donna K.
Baccarelli, Andrea A.
Benjamin, Emilia J.
Dehghan, Abbas

January 2016

BACKGROUND: Chronic low-grade inflammation reflects a subclinical immune response implicated in the ...

Additional file 3: Table S1. of Methylation patterns in serum DNA for early identification of disseminated breast cancer

Martin Widschwendter (184711)
Iona Evans (3429239)
Allison Jones (184670)
Shohreh Ghazali (4777599)
Daniel Reisel (4777605)
Andy Ryan (3340164)
Aleksandra Gentry-Maharaj (205215)
Michal Zikan (184682)
David Cibula (184688)
Johannes Eichner (236560)
Marianna Alunni-Fabbroni (4543465)
Julian Koch (4054624)
Wolfgang Janni (61953)
Tobias Paprotka (4777602)
Timo Wittenberger (4777596)
Usha Menon (205216)
Benjamin Wahl (606649)
Brigitte Rack (61954)
Harri LempiĂ¤inen (4777608)

December 2017

Coordinates and primers used to amplify the identified target regions using bisulfite sequencing. (P...

Additional file 2: Table S8. of Genome-wide DNA methylation analysis of transient neonatal diabetes type 1 patients with mutations in ZFP57

Mads Bak (181535)
Susanne Boonen (3420221)
Christina Dahl (3530879)
Johanne Hahnemann (3530867)
Deborah Mackay (3530870)
Zeynep TĂźmer (3530864)
Karen GrĂ¸nskov (3530876)
I. Temple (3530873)
Per Guldberg (551836)
Niels Tommerup (118532)

April 2016

Hypo- and hypermethylated regions detected in at least 2 patients. Additionally, the following chara...

Additional file 1: Table S1. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Abstract

Extracted data

Additional file 1: Table S1. of DNA methylation signatures of chronic low-grade inflammation are associated with complex diseases

Abstract

Extracted data

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