Levels of 24S-, 25-, and 27-OHC in the CSF and serum of patients.

<p>Among the levels of OHC_CSF (A-C) and OHC_serum (D-F), the levels 25- and 27-OHC_CSF were increased in patients with NMO compared with controls (B and C). The levels of 24S-OHC_CSF (A) and OHC_Serum levels did not differ between groups (D–F). The ratio of 27-OHC_CSF over 24S-OHC_CSF, which could be associated with either the disruption of the BBB or increased synthesis of 27-OHC in the CNS, was also increased in the NMO group (G). *<i>p</i> < 0.001; <i>n</i>.<i>s</i>. = not significant.