Effect of bed net-based interventions on the adult female mosquito population and individual age classes.

<p><b>(A)</b> The adult female mosquito population varies non-linearly under increasing coverage with different DBH doses (pink lines) or insecticide efficacy (blue lines). The vertical yellow bar indicates 85% coverage, which results in the largest female adult population and for which the age composition of the population is considered in (B). The population size shown is relative to the total female population in the absence of any interventions (black line). <b>(B)</b> The age composition of female mosquitoes in the presence of 2.0 μg DBH (pink) or the absence of any intervention (gray) at 85% coverage, indicated by a yellow bar in (A) and (C). The highlighted days in the x-axis indicate the age range of mosquitoes that are old enough to transmit malaria if infected. <b>(C)</b> The potentially infectious adult mosquito population under increasing levels of coverage with different DBH doses (pink lines) or insecticide efficacy (blue lines). This includes females at least 12 days after a blood meal, and in the case of DBH exposure, a proportion of these females are excluded due to reduced <i>Plasmodium</i> susceptibility. The yellow bar indicates 85% coverage, for which the age composition of the population is considered in (B). Without intervention, the proportion of mosquitoes at least 12 days after their first feed (black line) is 0.22. Insecticide of 60%, 80%, or 100% efficacy and DBH of experimentally determined efficacy (<a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1006060#ppat.1006060.g001" target="_blank">Fig 1</a>) are used.