<i>L</i>. <i>infantum</i> infection induces cell survival and apoptosis inhibition.

<p>U937-derived macrophages were infected with <i>L</i>. <i>infantum</i> promastigotes for 18 h. Infected and non-infected cells were treated with 0.5 μg/ml tunicamycin for 1 h, 2 h and 4 h. A) The Akt phosphorylation and cleavage of caspase-3 were analyzed in total cell lysates by western blotting. B) Band density quantification was performed using a Chemi-Doc System. Results are representative of three experiments. * p < 0.05, two-way ANOVA followed by Bonferroni post hoc test.