<i>Ex-vivo</i> porcine wound healing models cultured under euglycaemic, hyperglycaemic and hyperosmolar conditions.

<p>(A) Length of the regenerated epidermis for the experimental settings with and without preincubation for 48 h prior to wounding under euglycaemic (6 mM glucose), hyperglycaemic (50 mM glucose) and hyperosmolar (6 mM glucose + 44 mM mannitol) conditions 48 h after wounding. n = 8 in triplicates; mean ± SEM; *: statistically significant with p < 0.05; (B) Yellow coloring of the skin biopsies cultured under hyperglycaemic conditions for a total of 96 h (48 h preincubation and 48 h after wounding).