<p>(a) A maximum intensity projection of two budding <i>Y</i>. <i>lipolytica</i> Po1g cells, indicating two lipid-content phenotypes, namely: <i>large-but-fewer</i> LDs and <i>small-but-more</i> LDs. (b) A single Po1g cell trapped in the microfluidic system under continuous laminar flow at 1 μL/min. (c) Single-cell longitudinal time traces of the number of cytosolic LDs (N<sub>i</sub>), their median area (α<sub>i</sub>) and the percentage of lipid content (S<sub>i</sub>); 10 single-cell traces are illustrated, in varying colors consecutively. (d) Time-lapse 3D imaging of neutral lipid fluctuations (N<sub>i</sub>, α<sub>i</sub>, S<sub>i</sub>) of a single Po1g cell.</p
Quantitative characterization of a single-cell phenotype remains challenging. We combined a scalable...
Abstract This study aims to understand and better control the main biological mechani...
International audienceBACKGROUND: Lipid droplets (LD) are organelles with an important role in norma...
<p>(a) A scatter plot of the lipid flux (dS<sub>i</sub>(t)/dt) as a function of the total lipid cont...
Despite substantial achievements in elucidating the metabolic pathways of lipogenesis, a mechanistic...
<p>Similar to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0168889#pone.016...
Despite substantial achievements in elucidating the metabolic pathways of lipogenesis, a mechanistic...
Yarrowia lipolytica is an oleaginous ascomycete yeast that accumulates large amounts of lipids and h...
International audienceYarrowia lipolytica, with a diverse array of biotechnological applications, is...
Bioprocess limitations imposed by microbial cell-to-cell phenotypic diversity remain poorly understo...
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only. Several biotechnol...
<p>(A) Wild-type <i>Y</i>. <i>lipolytica</i> (ATCC 20460<sup>TM</sup>) was grown in YNB-R medium for...
© 2019, The Author(s). Optimal metabolic trade-offs between growth and productivity are key constrai...
Background: Yarrowia lipolytica is a non-conventional yeast that is extensively investigated for its...
International audienceAbstract Transient gene expression (TGE) technology enables the rapid producti...
Quantitative characterization of a single-cell phenotype remains challenging. We combined a scalable...
Abstract This study aims to understand and better control the main biological mechani...
International audienceBACKGROUND: Lipid droplets (LD) are organelles with an important role in norma...
<p>(a) A scatter plot of the lipid flux (dS<sub>i</sub>(t)/dt) as a function of the total lipid cont...
Despite substantial achievements in elucidating the metabolic pathways of lipogenesis, a mechanistic...
<p>Similar to <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0168889#pone.016...
Despite substantial achievements in elucidating the metabolic pathways of lipogenesis, a mechanistic...
Yarrowia lipolytica is an oleaginous ascomycete yeast that accumulates large amounts of lipids and h...
International audienceYarrowia lipolytica, with a diverse array of biotechnological applications, is...
Bioprocess limitations imposed by microbial cell-to-cell phenotypic diversity remain poorly understo...
© COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only. Several biotechnol...
<p>(A) Wild-type <i>Y</i>. <i>lipolytica</i> (ATCC 20460<sup>TM</sup>) was grown in YNB-R medium for...
© 2019, The Author(s). Optimal metabolic trade-offs between growth and productivity are key constrai...
Background: Yarrowia lipolytica is a non-conventional yeast that is extensively investigated for its...
International audienceAbstract Transient gene expression (TGE) technology enables the rapid producti...
Quantitative characterization of a single-cell phenotype remains challenging. We combined a scalable...
Abstract This study aims to understand and better control the main biological mechani...
International audienceBACKGROUND: Lipid droplets (LD) are organelles with an important role in norma...