<p>(A) Data are presented as mean total lesion size (mm<sup>2</sup>) ± SEM and are representative of 3 independent experiments with at least 4 mice/group. * p < 0.05; ** p < 0.01 (B) Photographs of representative lesions at day 7 after staphylococcal infection. Black bars indicate 10 mm. Abbreviations: WT = wild-type; Δ<i>tirS</i> = deleted for the <i>tirS</i> gene; Δ<i>tirS</i> + <i>tirS</i> = Δ<i>tirS</i> strain chromosomally restored for <i>tirS</i> gene.</p
<p><b>A.</b> Photograph of skin lesions caused by <i>S.aureus</i> at 3 days after <i>S.aureus</i> in...
<p>Mice (n = 4) were immunized with the octa-valent vaccine containing IsaA-His<sub>6</sub>, LytM-Hi...
<p>Wild type and athymic nude mice from the Balb/c background (n=10 mice/group) were sacrificed 3 da...
<p>Data are presented as mean total lesion size (mm<sup>2</sup>) ± SEM and are representative of 2 i...
<p>(A) Athymic nude mice from the Balb/c background had smaller lesions, compared wild type Balb/c m...
<p>Mice were infected with 1×10<sup>7</sup> CFU of <i>S. aureus</i> strains 923, 923<i>Δagr</i>, or ...
<p>BABL/c mice (n = 10) were passively immunized intraperitoneally (IP) anti-AT mAb 2A3 (10 mg/kg) (...
<p>BALB/c mice (n = 10) were infected intradermally (ID) with 5×10<sup>7</sup> cfu WT (□) or Δ<i>hla...
Staphylococcus aureus is the leading cause of skin infections. In a mouse model of S. aureus skin in...
(Ai) Representative images of dermonecrotic lesion size in mice (BALB/cJ) after 6 days postinfection...
<p>(A) Fluorescence confocal imaging of humanized mouse spleen showing separate mouse CD45 and human...
<p>(A) There was no difference in lesion size between C57Bl/6j (wild type) and TCR βδ (-/-) mice aft...
Staphylococcus aureus is the leading cause of skin infections. In a mouse model of S. aureus skin in...
<p>Median fluorescence intensity (MFI) values reflect levels of IgG against 25 <i>S</i>. <i>aureus</...
<p>NMRI mice (13-14/group) inoculated with a high dose of <i>Staphylococcus aureus</i> SH1000 (4.7–5...
<p><b>A.</b> Photograph of skin lesions caused by <i>S.aureus</i> at 3 days after <i>S.aureus</i> in...
<p>Mice (n = 4) were immunized with the octa-valent vaccine containing IsaA-His<sub>6</sub>, LytM-Hi...
<p>Wild type and athymic nude mice from the Balb/c background (n=10 mice/group) were sacrificed 3 da...
<p>Data are presented as mean total lesion size (mm<sup>2</sup>) ± SEM and are representative of 2 i...
<p>(A) Athymic nude mice from the Balb/c background had smaller lesions, compared wild type Balb/c m...
<p>Mice were infected with 1×10<sup>7</sup> CFU of <i>S. aureus</i> strains 923, 923<i>Δagr</i>, or ...
<p>BABL/c mice (n = 10) were passively immunized intraperitoneally (IP) anti-AT mAb 2A3 (10 mg/kg) (...
<p>BALB/c mice (n = 10) were infected intradermally (ID) with 5×10<sup>7</sup> cfu WT (□) or Δ<i>hla...
Staphylococcus aureus is the leading cause of skin infections. In a mouse model of S. aureus skin in...
(Ai) Representative images of dermonecrotic lesion size in mice (BALB/cJ) after 6 days postinfection...
<p>(A) Fluorescence confocal imaging of humanized mouse spleen showing separate mouse CD45 and human...
<p>(A) There was no difference in lesion size between C57Bl/6j (wild type) and TCR βδ (-/-) mice aft...
Staphylococcus aureus is the leading cause of skin infections. In a mouse model of S. aureus skin in...
<p>Median fluorescence intensity (MFI) values reflect levels of IgG against 25 <i>S</i>. <i>aureus</...
<p>NMRI mice (13-14/group) inoculated with a high dose of <i>Staphylococcus aureus</i> SH1000 (4.7–5...
<p><b>A.</b> Photograph of skin lesions caused by <i>S.aureus</i> at 3 days after <i>S.aureus</i> in...
<p>Mice (n = 4) were immunized with the octa-valent vaccine containing IsaA-His<sub>6</sub>, LytM-Hi...
<p>Wild type and athymic nude mice from the Balb/c background (n=10 mice/group) were sacrificed 3 da...