Radiation activates the DSB DNA response pathway in <i>Egr1</i>^<i>+/+</i> and <i>Egr1</i>^-/- BM-MNCs.

<p><b>(A)</b> Left: γ-H2AX protein expression by immunoblotting in irradiated BM-MNCs 30’, 45’ and 60’ after radiation exposure (2 Gy or 6 Gy). Right: Intensities of γ-H2AX bands were normalized to β-actin and are expressed as densitometric ratios. <b>(B)</b> Left: p-Chk2 protein expression by immunoblotting in irradiated BM-MNCs at different times after radiation exposure (2 Gy or 6 Gy). Right: p-Chk2 band intensities were normalized to those of GAPDH and are expressed as densitometric ratios. Results are representative of two experiments.