Additional file 2: of Regulatory T cells and IL10 suppress pulmonary host defense during early-life exposure to radical containing combustion derived ultrafine particulate matter

Depletion of Tregs in neonatal mice. (A) Timeline for DCB exposure and administration of LEAF purified monoclonal anti-CD25 antibody (PC61 clone). (B), (C) Anti-CD25 antibody administration significantly decreased pulmonary Tregs at 4 and 10 dpe, respectively. *p < 0.01 vs DCB/Isotype ctrl. Means ± SEM are plotted. Student’s t-test. (TIF 232 kb