Additional file 2: Figure S2. of Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration

Spinal motor neuron axonal outgrowth is not affected. (A) Spinal motor neuron axon of GA80-GFP fish (Gal4 driver + UAS:ATG-80xGGGGCC-GFP responder) and the GFP negative siblings (Gal4 driver or UAS:ATG-80xGGGGCC-GFP alone, or wild-type) at 28 hpf. (B) Length of outgrowing spinal motor neuron axons measured from the exit point of the spinal cord to the tip of the growth cone in the 5 somites anterior of the end of the yolk expansion at 28 hpf (indicated by the numbers 1–5). Embryos are sorted by the genotypes wild-type, driver, responder, and driver + responder. Statistical analyses was performed in indicated genotypes. Scale bar 20 μm. Mean ± SD. (PDF 4905 kb