Dynamics of HbA_1c during 8 weeks post whole blood donation (Tosoh G8).

<p>Horizontal dotted lines represent the Tosoh G8 one-tailed RCV (-4.28%) calculated for SI units. <i>A</i>: 23 non-diabetic blood donors after 475 mL whole blood donation. A low maximum % reduction in HbA_1c correlated with an early time point in the study, a high maximum % reduction in HbA_1c correlated with a late time point (Spearman r = -0.668; <i>P</i> = 0.0005). <i>B</i>: Individual changes of HbA_1c in 23 non-diabetic blood donors. The orange lines represent non-diabetic blood donors with low ferritin (<30 μg/L). <i>C</i>: 17 blood donors with type 2 diabetes after 475 mL whole blood donation. A low maximum % reduction in HbA_1c correlated with an early time point in the study, a high maximum % reduction in HbA_1c correlated with a late time point (Spearman r = -0.547; <i>P</i> = 0.015). <i>D</i>: Individual changes of HbA_1c in 17 blood donors with type 2 diabetes. The orange lines represent blood donors with type 2 diabetes with low ferritin (<30 μg/L).