<p>The alteration to oxidative stress levels was assessed following ‘priming’ with <i>W</i>. <i>somnifera</i> from 1 μg/mL to 10 μg/mL 48 h prior to 100 μM cisplatin treatment in <b>(A)</b> MDA-MB231, <b>(B)</b> HT-29 and <b>(C)</b> MCF10A cells. The bold line in each graph represents control treatment levels for the experiment Data represents the average of 5 independent experiments ± SEM. *p<0.05, **p<0.01, ***p<0.001 <i>vs</i> non-treatment, # p<0.05, ## p<0.01, ### p<0.001 <i>vs</i> cisplatin.</p
<p>Cells (2×10<sup>5</sup> cells/well) were exposed for 24 h to oxaliplatin (OXA) (50, 100 or 200 µM...
<p>Changes in BMF gene expression between OXA treated (T) and non-treated (NT) HT29, siPKM2- HT29 an...
<p>ALADIN knock-down and over-expression in stably transfected NCI-H295R1-TR was induced by 48 h tre...
<p>Cell viability was assessed following ‘priming’ with <i>W</i>. <i>somnifera</i> root extract (1 μ...
<p>Cells were treated with increasing concentrations (1 μg/mL <i>-</i>10 μg/mL) of <i>W</i>. <i>somn...
<p>Neuronal cultures were exposed to siRNAs on days 3-5 in culture then exposed to various concentra...
<p>Mice were repeatedly injected i.p. with 7 mg/kg oxaliplatin (OXA) at days 1, 2, 5 and 6 (28 mg/kg...
<p>Photos of WT and transgenic lines after MV (A) and H<sub>2</sub>O<sub>2</sub> (B) treatments. The...
<p>(<b>A</b>) mCat and isogenic Ctrl cells were exposed to cisplatin (12 μM) for 24 h and ROS level...
<p>Representative flow cytometry curves of total intracellular ROS levels (H<sub>2</sub>DCFDA) in (<...
<p>The top panels (A) show representative immunohistochemical staining for 8-oxoG DNA adducts in con...
Withania somnifera extracts are known for their anti-cancerous, anti-inflammatory and antioxidative ...
<p>(A) Twenty-four hours after exposure to diverse concentrations of H<sub>2</sub>O<sub>2</sub> for ...
<p>Intracellular ROS levels of C13* cells of different treatment groups were detected by Reactive Ox...
Objectives: Cisplatin is a powerful chemotherapeutic drug that is used to treatment a wide variety o...
<p>Cells (2×10<sup>5</sup> cells/well) were exposed for 24 h to oxaliplatin (OXA) (50, 100 or 200 µM...
<p>Changes in BMF gene expression between OXA treated (T) and non-treated (NT) HT29, siPKM2- HT29 an...
<p>ALADIN knock-down and over-expression in stably transfected NCI-H295R1-TR was induced by 48 h tre...
<p>Cell viability was assessed following ‘priming’ with <i>W</i>. <i>somnifera</i> root extract (1 μ...
<p>Cells were treated with increasing concentrations (1 μg/mL <i>-</i>10 μg/mL) of <i>W</i>. <i>somn...
<p>Neuronal cultures were exposed to siRNAs on days 3-5 in culture then exposed to various concentra...
<p>Mice were repeatedly injected i.p. with 7 mg/kg oxaliplatin (OXA) at days 1, 2, 5 and 6 (28 mg/kg...
<p>Photos of WT and transgenic lines after MV (A) and H<sub>2</sub>O<sub>2</sub> (B) treatments. The...
<p>(<b>A</b>) mCat and isogenic Ctrl cells were exposed to cisplatin (12 μM) for 24 h and ROS level...
<p>Representative flow cytometry curves of total intracellular ROS levels (H<sub>2</sub>DCFDA) in (<...
<p>The top panels (A) show representative immunohistochemical staining for 8-oxoG DNA adducts in con...
Withania somnifera extracts are known for their anti-cancerous, anti-inflammatory and antioxidative ...
<p>(A) Twenty-four hours after exposure to diverse concentrations of H<sub>2</sub>O<sub>2</sub> for ...
<p>Intracellular ROS levels of C13* cells of different treatment groups were detected by Reactive Ox...
Objectives: Cisplatin is a powerful chemotherapeutic drug that is used to treatment a wide variety o...
<p>Cells (2×10<sup>5</sup> cells/well) were exposed for 24 h to oxaliplatin (OXA) (50, 100 or 200 µM...
<p>Changes in BMF gene expression between OXA treated (T) and non-treated (NT) HT29, siPKM2- HT29 an...
<p>ALADIN knock-down and over-expression in stably transfected NCI-H295R1-TR was induced by 48 h tre...