<p>(A-D) The binding of the indicated ligands to the HIV-1<sub>JR-FL</sub> Env(-)Δ808 glycoprotein in NDs (glutaraldehyde-crosslinked), liposomes (crosslinked), in brain lipids/CHAPSO, in Cymal-6, or in detergent-free conditions was measured by ELISA. The ligands are highlighted as described in the <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0170672#pone.0170672.g006" target="_blank">Fig 6</a> legend. * = p < 0.05, unpaired t-test.</p
The human immunodeficiency virus type 1 (HIV-1) utilizes multiple cell surface molecules to mediate ...
<p>ELISA (panel A) and flow cytometry (B-D) were used to evaluate the binding of DVD-Igs to Env. <i>...
The HIV-1 envelope glycoprotein (Env) spike is challenging to study at the molecular level, due in p...
<p>(A,B) Binding of the indicated ligands to the HIV-1<sub>JR-FL</sub> Env(-)Δ808-NDs that had been ...
<p>(A) The epitopes on the HIV-1 Env trimer recognized by the monoclonal antibodies used in this stu...
<p>(A) A diagram of the wild-type (WT) HIV-1 Env is shown, with the signal sequence (S), gp120-gp41 ...
<p>The binding of each of the indicated ligands to the HIV-1<sub>BG505</sub> ΔCT Env variants expres...
<p>HIV-1<sub>LAI-JR-FL</sub> MC, produced in 293T cells, was incubated for 0 h, 4 h, 8 h, 24 h, or 9...
<p>The binding of PGT121 (<b>A</b>) and PG9 (<b>B</b> and <b>C</b>) to HIV-1<sub>BG505</sub> Env ΔCT...
<p>(A) Microscale thermophoresis profiles of the interaction of the 2G12 and 4E10 antibodies with HI...
The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contri...
The HIV-1 envelope glycoprotein (Env) spike is challenging to study at the molecular level, due in p...
<p>(A) Schematic diagram of negative selection of Env-NDs with the weakly neutralizing b6 antibody. ...
(A) Binding to 293T cells transfected with an empty pcDNA3.1 plasmid or increasing concentrations of...
<p>JRFL-pseudotyped HIV-1 was incubated for 2 h with peptidoliposomes in the presence or absence of ...
The human immunodeficiency virus type 1 (HIV-1) utilizes multiple cell surface molecules to mediate ...
<p>ELISA (panel A) and flow cytometry (B-D) were used to evaluate the binding of DVD-Igs to Env. <i>...
The HIV-1 envelope glycoprotein (Env) spike is challenging to study at the molecular level, due in p...
<p>(A,B) Binding of the indicated ligands to the HIV-1<sub>JR-FL</sub> Env(-)Δ808-NDs that had been ...
<p>(A) The epitopes on the HIV-1 Env trimer recognized by the monoclonal antibodies used in this stu...
<p>(A) A diagram of the wild-type (WT) HIV-1 Env is shown, with the signal sequence (S), gp120-gp41 ...
<p>The binding of each of the indicated ligands to the HIV-1<sub>BG505</sub> ΔCT Env variants expres...
<p>HIV-1<sub>LAI-JR-FL</sub> MC, produced in 293T cells, was incubated for 0 h, 4 h, 8 h, 24 h, or 9...
<p>The binding of PGT121 (<b>A</b>) and PG9 (<b>B</b> and <b>C</b>) to HIV-1<sub>BG505</sub> Env ΔCT...
<p>(A) Microscale thermophoresis profiles of the interaction of the 2G12 and 4E10 antibodies with HI...
The high variability of the HIV envelope glycoproteins (Env), and their heavy glycan coating, contri...
The HIV-1 envelope glycoprotein (Env) spike is challenging to study at the molecular level, due in p...
<p>(A) Schematic diagram of negative selection of Env-NDs with the weakly neutralizing b6 antibody. ...
(A) Binding to 293T cells transfected with an empty pcDNA3.1 plasmid or increasing concentrations of...
<p>JRFL-pseudotyped HIV-1 was incubated for 2 h with peptidoliposomes in the presence or absence of ...
The human immunodeficiency virus type 1 (HIV-1) utilizes multiple cell surface molecules to mediate ...
<p>ELISA (panel A) and flow cytometry (B-D) were used to evaluate the binding of DVD-Igs to Env. <i>...
The HIV-1 envelope glycoprotein (Env) spike is challenging to study at the molecular level, due in p...