The effect of co-conservation and co-evolution on the interface prediction.

<p>Left: The fraction of proteins for which a near-native decoy is in the top scored predictions, as a function of the number of decoys considered, for the <i>S</i>(<i>S</i>^RP, <i>S</i>^N, <i>S</i>^ent) (grey solid line), <i>S</i>(<i>S</i>^RP, <i>S</i>^N, <i>S</i>^ent, <i>S</i>^CMM (black solid line), <i>S</i>(<i>S</i>^RP, <i>S</i>^N, <i>S</i>^ent, <i>S</i>^CT (grey dashed line), <i>S</i>(<i>S</i>^RP, <i>S</i>^N, <i>S</i>^ent, <i>S</i>^CT, <i>S</i>^CMM) (black dashed line) and (light grey dash-dotted line) scoring functions. Right: The number of proteins for which the rank of the top near-native prediction is within the top 1, 5 or 10 predictions, for the <i>S</i>(<i>S</i>^RP, <i>S</i>^N, <i>S</i>^ent) (solid black bars), <i>S</i>(<i>S</i>^RP, <i>S</i>^N, <i>S</i>^ent, <i>S</i>^CMM (solid grey bars), <i>S</i>(<i>S</i>^RP, <i>S</i>^N, <i>S</i>^ent, <i>S</i>^CT (dark checked bars) and <i>S</i>(<i>S</i>^RP, <i>S</i>^N, <i>S</i>^ent, <i>S</i>^CT, <i>S</i>^CMM) (light checked bars) scoring functions.